a-Dendrotoxin

Material Safety Data Sheet
Customer
Order Number
Number
Section 1. Chemical Product and Company Identification
Common Name a l p h a - D e n d r o t o x i n , Dendroaspis 253704
Catalog #
angusticeps
Calbiochem-Novabiochem Corp.
Supplier In Case of Call Chemtrec?
10394 Pacific Center Court
Emergency (800)424-9300 (within U.S.A.)
San Diego, CA 92121
(703)527-3887 (outside U.S.A.)
(858)450-5558/(800)854-3417
FAX: (858)453-3552

alpha-DTx
Synonym




Section 2. Composition, Information on Ingredients
CAS #
Name Exposure Limits

1) alpha-Dendrotoxin, Dendroaspis angusticeps 144637-68-3 Not available.


Section 3. Hazards Identification
Solid.
Physical State and
Appearance

CAUTION!
Emergency Overview
MAY BE HARMFUL IF INHALED, ABSORBED THROUGH SKIN OR SWALLOWED.
MAY CAUSE DAMAGE TO THE FOLLOWING ORGANS: EYES, MUSCLE TISSUE, THROAT, TRACHEA.
Avoid prolonged contact with eyes, skin, and clothing. Do not ingest. Avoid breathing dust. Keep container
closed. Use only with adequate ventilation. Wash thoroughly after handling.
Absorbed through skin. Dermal contact. Inhalation. Ingestion.
Routes of Entry

Potential Acute Health Effects
Eyes Not available.

Skin Hazardous in case of skin contact (permeator).

Inhalation Hazardous in case of inhalation.

Ingestion Hazardous in case of ingestion.

CARCINOGENIC EFFECTS : Not available.
Potential Chronic Health
MUTAGENIC EFFECTS: Not available.
Effects
TERATOGENIC EFFECTS: Not available.
Repeated or prolonged exposure is not known to aggravate medical condition.
Medical Conditions
Aggravated by Overexposure:
Not available.
Overexposure
/Signs/Symptoms
See Toxicological Information (section 11)




253704 Catalog #
 Section 4. First Aid Measures
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for
Eye Contact
at least 15 minutes. Cold water may be used. Get medical attention.
In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes.
Skin Contact
Cold water may be used.Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical
attention.
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Inhalation
Get medical attention.
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
Ingestion
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen
tight clothing such as a collar, tie, belt or waistband.
Notes to Physician Not available.


Section 5. Fire Fighting Measures
May be combustible at high temperature.
Flammability of the Product

Not available.
Flash Points

These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), sulfur oxides (SO2, SO3...).
Products of Combustion


Not available.
Fire Hazards in Presence of
Various Substances

Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
of Various Substances

SMALL FIRE: Use DRY chemical powder.
Fire Fighting Media
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
and Instructions

Be sure to use an approved/certified respirator or equivalent.
Protective Clothing (Fire)


Not available.
Special Remarks on Fire
Hazards
Special Remarks on Explosion Not available.
Hazards

Section 6. Accidental Release Measures
Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by
Small Spill and Leak
spreading water on the contaminated surface and dispose of according to local and regional authority
requirements.
Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading
Large Spill and Leak
water on the contaminated surface and allow to evacuate through the sanitary system.

Section 7. Handling and Storage
Avoid prolonged contact with eyes, skin, and clothing. Do not ingest. Avoid breathing dust. Keep container
Handling
closed. Use only with adequate ventilation. Wash thoroughly after handling.
Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above -20??C
Storage
(-4??F).




253704 Catalog #
 Section 8. Exposure Controls, Personal Protection
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
Engineering Controls
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep
exposure to airborne contaminants below the exposure limit.
Personal Protection
Eyes Safety glasses.

Body Lab coat.

Respiratory Dust respirator. Be sure to use an approved/certified respirator or equivalent.

Hands Gloves.
Feet Not applicable.

Protective Clothing
(Pictograms)




Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self-contained breathing apparatus should be
used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a
a Large Spill
specialist BEFORE handling this product.
Exposure Limits
Product Name
Not available.
1) alpha-Dendrotoxin

Consult local authorities for acceptable exposure limits.


Section 9. Physical and Chemical Properties
Solid.
Physical State and Not available.
Color
Appearance
7048.1 g/mole
Molecular Weight

C305H472N98O84S6
Molecular Formula

Not available.
Boiling/Condensation Point

Not available.
Melting/Freezing Point

Not available.
Specific Gravity

Not applicable.
Vapor Pressure

Not available.
Vapor Density

Easily soluble in cold water.
Solubility



Section 10. Stability and Reactivity
The product is stable.
Stability and Reactivity

Not available.
Incompatibility with Various
Substances
Not available.
Hazardous Decomposition
Products
Not available.
Hazardous Polymerization




253704 Catalog #
 Section 11. Toxicological Information
RTECS # HF9298000

Toxicity to Animals LD50: Not available.
LC50: Not available.
May cause damage to the following organs: eyes, muscle tissue, throat, traechea.
Chronic Effects on Humans

Other Toxic Effects on Hazardous in case of skin contact (permeator), of ingestion, of inhalation.
Humans

Special Remarks on Toxicity to Not available.
Animals

Special Remarks on Chronic May be fatal, if the substance enters bloodstream.
Effects on Humans

To the best of our knowledge, the toxicological properties of this product have not been thoroughly
Special Remarks on Other
investigated.
Toxic Effects on Humans


Section 12. Ecological Information
Not available.
Ecotoxicity

The products of degradation are less toxic than the product itself.
Toxicity of the Products of
Biodegradation


Section 13. Disposal Considerations
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Waste Information

Not available.
Waste Stream
Consult your local or regional authorities.

Section 14. Transport Information
Not a DOT controlled material (United States).
DOT Classification



Not regulated.

Not controlled under TDG (Canada).
TDG Classification



Not regulated.


Not available.
Marine Pollutant




Not applicable.
Special Provisions for
Transport
Not controlled under ADR (Europe).
ADR/RID Classification

Not controlled under IMDG.
IMO/IMDG Classification

Not controlled under IATA.
ICAO/IATA Classification


253704 Catalog #
 Section 15. Regulatory Information
CLASS: Target organ effects.
HCS Classification

TSCA: No products were found.
U.S. Federal Regulations
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found.
SARA 313 toxic chemical notification and release reporting: No products were found.
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean air act (CAA) 112 accidental release prevention: No products were found.
Clean air act (CAA) 112 regulated flammable substances: No products were found.
Clean air act (CAA) 112 regulated toxic substances: No products were found.
Not controlled under WHMIS (Canada).
WHMIS (Canada)

No products were found.

International Regulations
Not available.
EINECS

R20/21/22- Harmful by inhalation, in contact with skin and if swallowed.
DSCL (EEC)

No products were found.
International Lists

State Regulations No products were found.
California prop. 65: No products were found.


Section 16. Other Information
MAY BE HARMFUL IF INHALED, ABSORBED THROUGH SKIN OR SWALLOWED.
Label Requirements
MAY CAUSE DAMAGE TO THE FOLLOWING ORGANS: EYES, MUSCLE TISSUE, THROAT, TRACHEA.

Hazardous Material * 0 National Fire
Health
Fire Hazard
1
Information System 1 Protection Association
Fire Hazard
(U.S.A.) (U.S.A.) 0 0
Health Reactivity
0
Reactivity
Specific Hazard
E
Personal Protection




Notice to Reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named supplier nor any of its subsidiaries
assumes any liability whatsoever for the accuracy or completeness of the information contained herein.
Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used
with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist.

Date of issue
253704
Catalog # 12/19/2001.

;

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