*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : SG1593000
CHEMICAL NAME : Phenazinium,
3-amino-7-((p-(dimethylamino)phenyl)azo)-5-phenyl-,
chloride
CAS REGISTRY NUMBER : 4618-88-6
LAST UPDATED : 199410
DATA ITEMS CITED : 5
MOLECULAR FORMULA : C26-H23-N6.Cl
MOLECULAR WEIGHT : 455.00
WISWESSER LINE NOTATION : T C666 BK INJ BR& EZ MNUNR DN1&1 &G
COMPOUND DESCRIPTOR : Mutagen
SYNONYMS/TRADE NAMES :
* 3-Amino-7-((p-(dimethylamino)phenyl)azo)-5-phenylphenazinium chloride
* C.I. 11045
* Janus Green
* Janus Green G
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 18900 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - respiratory stimulation
Lungs, Thorax, or Respiration - other changes
REFERENCE :
SMBUA9 Stanford Medical Bulletin. (Palo Alto, CA) V.1-20, 1942-62.
Discontinued. Volume(issue)/page/year: 9,96,1951
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 12960 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - respiratory stimulation
Lungs, Thorax, or Respiration - other changes
REFERENCE :
SMBUA9 Stanford Medical Bulletin. (Palo Alto, CA) V.1-20, 1942-62.
Discontinued. Volume(issue)/page/year: 9,96,1951
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 4810 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - respiratory stimulation
Lungs, Thorax, or Respiration - other changes
REFERENCE :
SMBUA9 Stanford Medical Bulletin. (Palo Alto, CA) V.1-20, 1942-62.
Discontinued. Volume(issue)/page/year: 9,96,1951
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Yeast - Schizosaccharomyces pombe
DOSE/DURATION : 1 mg/L
REFERENCE :
MGGEAE Molecular and General Genetics. (Springer-Verlag, Heidelberger Pl.
3, D-1000 Berlin 33, Fed. Rep. Ger.) V.99- 1967-
Volume(issue)/page/year: 144,75,1976
*** STATUS IN U.S. ***
EPA GENETOX PROGRAM 1988, Negative: B subtilis rec assay
*** END OF RECORD ***
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