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Toluene-2,4-diamine

1.1

IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING

Product identifiers

Product name

Product Number

Brand

Index-No.

CAS-No.

2,4-Diaminotoluene

101915

Anonymous

612-099-00-3

95-80-7

1.2

Relevant identified uses of the substance or mixture and uses advised against

Identified uses

Laboratory chemicals, Manufacture of substances

2.1

2.2

HAZARDS IDENTIFICATION

Classification of the substance or mixture

Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]

Carcinogenicity (Category 1B)

Acute toxicity, Oral (Category 3)

Acute toxicity, Dermal (Category 4)

Specific target organ toxicity - repeated exposure (Category 2)

Skin sensitization (Category 1)

Chronic aquatic toxicity (Category 2)

Germ cell mutagenicity (Category 2)

Reproductive toxicity (Category 2)

Classification according to EU Directives 67/548/EEC or 1999/45/EC

May cause cancer. Possible risk of impaired fertility. Possible risk of irreversible effects. Toxic if swallowed.

Harmful in contact with skin. Harmful: danger of serious damage to health by prolonged exposure if

swallowed. May cause sensitization by skin contact. Toxic to aquatic organisms, may cause long-term

adverse effects in the aquatic environment.

Label elements

Labelling according Regulation (EC) No 1272/2008 [CLP]

Pictogram

Signal word

Hazard statement(s)

H301

Danger

Toxic if swallowed.

H312

H317

H341

H350

H361f

H373

H411

Precautionary statement(s)

P201

P273

P280

P301 + P310

P308 + P313

Supplemental Hazard

Harmful in contact with skin.

May cause an allergic skin reaction.

Suspected of causing genetic defects.

May cause cancer.

Suspected of damaging fertility.

May cause damage to organs through prolonged or repeated exposure.

Toxic to aquatic life with long lasting effects.

Obtain special instructions before use.

Avoid release to the environment.

Wear protective gloves/ protective clothing.

IF SWALLOWED: Immediately call a POISON CENTER or doctor/

physician.

IF exposed or concerned: Get medical advice/ attention.

none

Statements

Restricted to professional users.

According to European Directive 67/548/EEC as amended.

Hazard symbol(s)

R-phrase(s)

R45

R21

R25

R48/22

R68

R43

R51/53

R62

S-phrase(s)

S53

S45

S61

May cause cancer.

Also harmful in contact with skin.

Also toxic if swallowed.

Also harmful: danger of serious damage to health by prolonged exposure

if swallowed.

Possible risk of irreversible effects.

May cause sensitization by skin contact.

Toxic to aquatic organisms, may cause long-term adverse effects in the

aquatic environment.

Possible risk of impaired fertility.

Avoid exposure - obtain special instructions before use.

In case of accident or if you feel unwell, seek medical advice immediately

(show the label where possible).

Avoid release to the environment. Refer to special instructions/ Safety

data sheets.

Restricted to professional users.

2.3

3.1

Other hazards - none

COMPOSITION/INFORMATION ON INGREDIENTS

Substances

Synonyms

Formula

Molecular Weight

Component

2,4-Toluenediamine

4-Methyl-m-phenylenediamine

2,4-Toluenediamine

2,4-Diaminotoluene

4-Methyl-1,3-phenylenediamine

C7H10N2

122,17 g/mol

Concentration

CAS-No.

95-80-7

EC-No.

Index-No.

202-453-1

612-099-00-3

4.1

4.2

4.3

5.1

5.2

5.3

5.4

6.1

6.2

6.3

6.4

7.1

7.2

FIRST AID MEASURES

Description of first aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

Most important symptoms and effects, both acute and delayed

Liver injury may occur., Absorption into the body leads to the formation of methemoglobin which in

sufficient concentration causes cyanosis. Onset may be delayed 2 to 4 hours or longer.

Indication of any immediate medical attention and special treatment needed

no data available

FIREFIGHTING MEASURES

Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Special hazards arising from the substance or mixture

Carbon oxides, nitrogen oxides (NOx)

Advice for firefighters

Wear self contained breathing apparatus for fire fighting if necessary.

Further information

no data available

ACCIDENTAL RELEASE MEASURES

Personal precautions, protective equipment and emergency procedures

Wear respiratory protection. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate

ventilation. Evacuate personnel to safe areas. Avoid breathing dust.

Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the

environment must be avoided.

Methods and materials for containment and cleaning up

Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed

containers for disposal.

Reference to other sections

For disposal see section 13.

HANDLING AND STORAGE

Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols.Avoid exposure - obtain special

instructions before use.

Provide appropriate exhaust ventilation at places where dust is formed.

Conditions for safe storage, including any incompatibilities

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

7.3

8.1

8.2

9.1

Specific end uses

no data available

EXPOSURE CONTROLS/PERSONAL PROTECTION

Control parameters

Components with workplace control parameters

Exposure controls

Appropriate engineering controls

Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling

the product.

Personal protective equipment

Eye/face protection

Face shield and safety glasses Use equipment for eye protection tested and approved under

appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique

(without touching glove's outer surface) to avoid skin contact with this product. Dispose of

contaminated gloves after use in accordance with applicable laws and good laboratory practices.

Wash and dry hands.

The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and

the standard EN 374 derived from it.

Body Protection

Complete suit protecting against chemicals, The type of protective equipment must be selected

according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection

Where risk assessment shows air-purifying respirators are appropriate use a full-face particle

respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering

controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use

respirators and components tested and approved under appropriate government standards such

as NIOSH (US) or CEN (EU).

PHYSICAL AND CHEMICAL PROPERTIES

Information on basic physical and chemical properties

Appearance

Odour

Odour Threshold

Melting point/freezing

point

Initial boiling point and

boiling range

Flash point

Evaporation rate

Form: crystalline

Colour: dark brown

no data available

Melting point/range: 97 - 99 °C - lit.

283 - 285 °C - lit.

no data available

Flammability (solid, gas) no data available

Upper/lower

flammability or

explosive limits

Vapour pressure

no data available

Vapour density

no data available

m) Relative density

no data available

Water solubility

Partition coefficient: n-

octanol/water

Autoignition

temperature

Decomposition

temperature

Viscosity

Explosive properties

Oxidizing properties

no data available

9.2

10.

10.1

10.2

10.3

10.4

10.5

10.6

11.

11.1

Other safety information

no data available

STABILITY AND REACTIVITY

Reactivity

no data available

Chemical stability

no data available

Possibility of hazardous reactions

no data available

Conditions to avoid

no data available

Incompatible materials

Strong oxidizing agents

Hazardous decomposition products

Other decomposition products - no data available

TOXICOLOGICAL INFORMATION

Information on toxicological effects

Acute toxicity

LD50 Intraperitoneal - rat - 325 mg/kg

Skin corrosion/irritation

Skin - rabbit - Mild skin irritation - 24 h

Serious eye damage/eye irritation

Eyes - rabbit - Moderate eye irritation - 24 h

Respiratory or skin sensitization

no data available

May cause sensitization by inhalation.

Germ cell mutagenicity

no data available

Carcinogenicity

This product is or contains a component that has been reported to be probably carcinogenic based on its

IARC, OSHA, ACGIH, NTP, or EPA classification.

Possible human carcinogen

IARC:

2B - Group 2B: Possibly carcinogenic to humans (2,4-Toluenediamine)

Reproductive toxicity

Suspected human reproductive toxicant

Specific target organ toxicity - single exposure

no data available

Specific target organ toxicity - repeated exposure

no data available

Aspiration hazard

no data available

Potential health effects

Inhalation

Ingestion

Skin

Eyes

May be harmful if inhaled. May cause respiratory tract irritation.

Toxic if swallowed.

Harmful if absorbed through skin. May cause skin irritation.

Causes serious eye irritation.

Signs and Symptoms of Exposure

Liver injury may occur., Absorption into the body leads to the formation of methemoglobin which in

sufficient concentration causes cyanosis. Onset may be delayed 2 to 4 hours or longer.

Additional Information

RTECS: XS9625000

12.

12.1

ECOLOGICAL INFORMATION

Toxicity

Toxicity to fish

Toxicity to daphnia and

other aquatic

invertebrates

LC50 - Oryzias latipes - 912 mg/l - 96,0 h

EC50 - Daphnia magna (Water flea) - 1,6 mg/l - 48 h

12.2

12.3

12.4

12.5

12.6

13.

13.1

14.

14.1

Persistence and degradability

no data available

Bioaccumulative potential

no data available

Mobility in soil

no data available

Results of PBT and vPvB assessment

no data available

Other adverse effects

Toxic to aquatic life.

DISPOSAL CONSIDERATIONS

Waste treatment methods

Product

Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material

with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.

Contaminated packaging

Dispose of as unused product.

TRANSPORT INFORMATION

UN number

ADR/RID: 1709

IMDG: 1709

IATA: 1709

14.2

UN proper shipping name

ADR/RID:

IMDG:

IATA:

2,4-TOLUYLENEDIAMINE, SOLID

2,4-Toluylenediamine, solid

14.3

Transport hazard class(es)

14.4

14.5

14.6

15.

ADR/RID: 6.1

Packaging group

ADR/RID: III

Environmental hazards

ADR/RID: yes

Special precautions for user

no data available

REGULATORY INFORMATION

IMDG: 6.1

IMDG: III

IMDG Marine pollutant: yes

IATA: 6.1

IATA: III

IATA: no

This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.

15.1

15.2

16.

Safety, health and environmental regulations/legislation specific for the substance or mixture

no data available

Chemical Safety Assessment

no data available

OTHER INFORMATION

Further information

The above information is believed to be correct but does not purport to be all inclusive and
shall be used only as a guide. The information this document is based on the resent state
of our knowledge and is applicable to the product with regard to appropriate safety precautions.
It does not represent any guarantee of the properties of the product. Lookchem shall not be
held liable for any damage resulting from handling or from contact with the above product.
See reverse side of invoice or packing slip for additional terms and conditions of sale.

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