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Pyridine, 4-methyl-

1.1

IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING

Product identifiers

Product name

Product Number

Brand

Index-No.

CAS-No.

4-Picoline

239615

Anonymous

613-037-00-8

108-89-4

1.2

Relevant identified uses of the substance or mixture and uses advised against

Identified uses

Laboratory chemicals, Manufacture of substances

2.1

2.2

HAZARDS IDENTIFICATION

Classification of the substance or mixture

Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]

Flammable liquids (Category 3)

Acute toxicity, Dermal (Category 3)

Acute toxicity, Inhalation (Category 4)

Acute toxicity, Oral (Category 4)

Eye irritation (Category 2)

Specific target organ toxicity - single exposure (Category 3)

Skin irritation (Category 2)

Classification according to EU Directives 67/548/EEC or 1999/45/EC

Flammable. Toxic in contact with skin. Irritating to eyes, respiratory system and skin. Harmful by inhalation

and if swallowed.

Label elements

Labelling according Regulation (EC) No 1272/2008 [CLP]

Pictogram

Signal word

Hazard statement(s)

H226

H302

H311

H315

Danger

Flammable liquid and vapour.

Harmful if swallowed.

Toxic in contact with skin.

Causes skin irritation.

H319

H332

H335

Precautionary statement(s)

P261

P280

P305 + P351 + P338

P312

Supplemental Hazard

Causes serious eye irritation.

Harmful if inhaled.

May cause respiratory irritation.

Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.

Wear protective gloves/ protective clothing.

IF IN EYES: Rinse cautiously with water for several minutes. Remove

contact lenses, if present and easy to do. Continue rinsing.

Call a POISON CENTER or doctor/ physician if you feel unwell.

none

Statements

According to European Directive 67/548/EEC as amended.

Hazard symbol(s)

R-phrase(s)

R10

R20/22

R24

R36/37/38

S-phrase(s)

S26

S36

S45

Flammable.

Harmful by inhalation and if swallowed.

Toxic in contact with skin.

Irritating to eyes, respiratory system and skin.

In case of contact with eyes, rinse immediately with plenty of water and

seek medical advice.

Wear suitable protective clothing.

In case of accident or if you feel unwell, seek medical advice immediately

(show the label where possible).

2.3

3.1

Other hazards - none

COMPOSITION/INFORMATION ON INGREDIENTS

Substances

Synonyms

Formula

Molecular Weight

Component

4-Picoline

4-Methylpyridine

C6H7N

93,13 g/mol

Concentration

CAS-No.

EC-No.

Index-No.

108-89-4

203-626-4

613-037-00-8

4.1

FIRST AID MEASURES

Description of first aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with

water. Consult a physician.

4.2

4.3

5.1

5.2

5.3

5.4

6.1

6.2

6.3

6.4

7.1

7.2

7.3

8.1

8.2

Most important symptoms and effects, both acute and delayed

Liver injury may occur., Kidney injury may occur., Cough, Shortness of breath, Headache, Nausea,

Vomiting, Gastrointestinal disturbance

Indication of any immediate medical attention and special treatment needed

no data available

FIREFIGHTING MEASURES

Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Special hazards arising from the substance or mixture

Carbon oxides, nitrogen oxides (NOx)

Advice for firefighters

Wear self contained breathing apparatus for fire fighting if necessary.

Further information

Use water spray to cool unopened containers.

ACCIDENTAL RELEASE MEASURES

Personal precautions, protective equipment and emergency procedures

Wear respiratory protection. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove

all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form

explosive concentrations. Vapours can accumulate in low areas.

Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

Methods and materials for containment and cleaning up

Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and

place in container for disposal according to local regulations (see section 13).

Reference to other sections

For disposal see section 13.

HANDLING AND STORAGE

Precautions for safe handling

Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.

Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic

charge.

Conditions for safe storage, including any incompatibilities

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are

opened must be carefully resealed and kept upright to prevent leakage.

Specific end uses

no data available

EXPOSURE CONTROLS/PERSONAL PROTECTION

Control parameters

Components with workplace control parameters

Exposure controls

Appropriate engineering controls

Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling

the product.

Personal protective equipment

Eye/face protection

Face shield and safety glasses Use equipment for eye protection tested and approved under

appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique

(without touching glove's outer surface) to avoid skin contact with this product. Dispose of

contaminated gloves after use in accordance with applicable laws and good laboratory practices.

Wash and dry hands.

The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and

the standard EN 374 derived from it.

Body Protection

Complete suit protecting against chemicals, Flame retardant antistatic protective clothing, The type

of protective equipment must be selected according to the concentration and amount of the

dangerous substance at the specific workplace.

Respiratory protection

Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator

with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup

to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air

respirator. Use respirators and components tested and approved under appropriate government

standards such as NIOSH (US) or CEN (EU).

9.1

PHYSICAL AND CHEMICAL PROPERTIES

Information on basic physical and chemical properties

Appearance

Odour

Odour Threshold

Melting point/freezing

point

Initial boiling point and

boiling range

Flash point

Evaporation rate

Form: clear, liquid

Colour: light yellow

no data available

Melting point/range: 2,4 °C - lit.

145 °C - lit.

39 °C - closed cup

no data available

Flammability (solid, gas) no data available

Upper/lower

flammability or

explosive limits

Vapour pressure

Vapour density

Upper explosion limit: 8,7 %(V)

Lower explosion limit: 1,3 %(V)

7,69 hPa at 25 °C

5 hPa at 20 °C

3,22 - (Air = 1.0)

m) Relative density

0,957 g/cm3 at 25 °C

Water solubility

Partition coefficient: n-

octanol/water

Autoignition

temperature

Decomposition

temperature

completely miscible

log Pow: 1,22

no data available

Viscosity

Explosive properties

Oxidizing properties

no data available

9.2

10.

10.1

10.2

10.3

10.4

10.5

10.6

11.

11.1

Other safety information

no data available

STABILITY AND REACTIVITY

Reactivity

no data available

Chemical stability

no data available

Possibility of hazardous reactions

no data available

Conditions to avoid

Heat, flames and sparks.

Incompatible materials

Oxidizing agents

Hazardous decomposition products

Other decomposition products - no data available

TOXICOLOGICAL INFORMATION

Information on toxicological effects

Acute toxicity

LD50 Oral - rat - 440 mg/kg

LC50 Inhalation - mouse - 4.000 mg/m3

Skin corrosion/irritation

Skin - rabbit - Open irritation test

Serious eye damage/eye irritation

Eyes - rabbit - Moderate eye irritation - 24 h

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

IARC:

No component of this product present at levels greater than or equal to 0.1% is identified as

probable, possible or confirmed human carcinogen by IARC.

Reproductive toxicity

no data available

Specific target organ toxicity - single exposure

May cause respiratory irritation.

Specific target organ toxicity - repeated exposure

no data available

Aspiration hazard

no data available

Potential health effects

Inhalation

Ingestion

Skin

Harmful if inhaled. Causes respiratory tract irritation.

Harmful if swallowed.

Toxic if absorbed through skin. Causes skin irritation.

Eyes

Causes serious eye irritation.

Signs and Symptoms of Exposure

Liver injury may occur., Kidney injury may occur., Cough, Shortness of breath, Headache, Nausea,

Vomiting, Gastrointestinal disturbance

Additional Information

RTECS: UT5425000

12.

12.1

ECOLOGICAL INFORMATION

Toxicity

Toxicity to fish

LC50 - Pimephales promelas (fathead minnow) - 351 - 464 mg/l - 96 h

12.2

12.3

12.4

12.5

12.6

13.

13.1

14.

14.1

Persistence and degradability

no data available

Bioaccumulative potential

no data available

Mobility in soil

no data available

Results of PBT and vPvB assessment

no data available

Other adverse effects

no data available

DISPOSAL CONSIDERATIONS

Waste treatment methods

Product

Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting

as this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal

company.

Contaminated packaging

Dispose of as unused product.

TRANSPORT INFORMATION

UN number

14.2

ADR/RID: 2313

UN proper shipping name

IMDG: 2313

IATA: 2313

ADR/RID:

IMDG:

IATA:

PICOLINES (4-Picoline)

Picolines (4-Picoline)

14.3

Transport hazard class(es)

14.4

14.5

14.6

15.

ADR/RID: 3

Packaging group

ADR/RID: III

Environmental hazards

ADR/RID: no

Special precautions for user

no data available

REGULATORY INFORMATION

IMDG: 3

IMDG: III

IMDG Marine pollutant: no

IATA: 3

IATA: III

IATA: no

This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.

15.1

Safety, health and environmental regulations/legislation specific for the substance or mixture

no data available

15.2

16.

Chemical Safety Assessment

no data available

OTHER INFORMATION

Further information

The above information is believed to be correct but does not purport to be all inclusive and
shall be used only as a guide. The information this document is based on the resent state
of our knowledge and is applicable to the product with regard to appropriate safety precautions.
It does not represent any guarantee of the properties of the product. Lookchem shall not be
held liable for any damage resulting from handling or from contact with the above product.
See reverse side of invoice or packing slip for additional terms and conditions of sale.

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