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Benzene,2-isocyanato-1,3-bis(1-methylethyl)-

1.1

IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING

Product identifiers

Product name

Product Number

Brand

CAS-No.

2,6-Diisopropylphenyl isocyanate

308218

Anonymous

28178-42-9

1.2

Relevant identified uses of the substance or mixture and uses advised against

Identified uses

Laboratory chemicals, Manufacture of substances

2.1

2.2

HAZARDS IDENTIFICATION

Classification of the substance or mixture

Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]

Acute toxicity, Oral (Category 4)

Acute toxicity, Inhalation (Category 1)

Skin irritation (Category 2)

Serious eye damage (Category 1)

Respiratory sensitization (Category 1)

Skin sensitization (Category 1)

Specific target organ toxicity - single exposure (Category 3)

Classification according to EU Directives 67/548/EEC or 1999/45/EC

Very toxic by inhalation. Irritating to eyes, respiratory system and skin. May cause sensitization by

inhalation.

Label elements

Labelling according Regulation (EC) No 1272/2008 [CLP]

Pictogram

Signal word

Hazard statement(s)

H302

H315

H317

H318

H330

Danger

Harmful if swallowed.

Causes skin irritation.

May cause an allergic skin reaction.

Causes serious eye damage.

Fatal if inhaled.

H334

H335

Precautionary statement(s)

P260

P280

P284

P305 + P351 + P338

P310

Supplemental Hazard

May cause allergy or asthma symptoms or breathing difficulties if inhaled.

May cause respiratory irritation.

Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.

Wear protective gloves/ eye protection/ face protection.

Wear respiratory protection.

IF IN EYES: Rinse cautiously with water for several minutes. Remove

contact lenses, if present and easy to do. Continue rinsing.

Immediately call a POISON CENTER or doctor/ physician.

none

Statements

According to European Directive 67/548/EEC as amended.

Hazard symbol(s)

R-phrase(s)

R26

R36/37/38

R42

S-phrase(s)

S23

S26

S36/37/39

S45

Very toxic by inhalation.

Irritating to eyes, respiratory system and skin.

May cause sensitization by inhalation.

Do not breathe vapour.

In case of contact with eyes, rinse immediately with plenty of water and

seek medical advice.

Wear suitable protective clothing, gloves and eye/face protection.

In case of accident or if you feel unwell, seek medical advice immediately

(show the label where possible).

2.3

3.1

Other hazards

Lachrymator.

COMPOSITION/INFORMATION ON INGREDIENTS

Substances

Formula

Molecular Weight

Component

C13H17NO

203,28 g/mol

Concentration

2,6-Diisopropylphenyl isocyanate

CAS-No.

EC-No.

28178-42-9

248-885-4

4.1

FIRST AID MEASURES

Description of first aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2

4.3

5.1

5.2

5.3

5.4

6.1

6.2

6.3

6.4

7.1

7.2

7.3

8.1

8.2

Most important symptoms and effects, both acute and delayed

Cough, Shortness of breath, Headache, Nausea, Vomiting, To the best of our knowledge, the chemical,

physical, and toxicological properties have not been thoroughly investigated.

Indication of any immediate medical attention and special treatment needed

no data available

FIREFIGHTING MEASURES

Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Special hazards arising from the substance or mixture

Carbon oxides, nitrogen oxides (NOx)

Advice for firefighters

Wear self contained breathing apparatus for fire fighting if necessary.

Further information

no data available

ACCIDENTAL RELEASE MEASURES

Personal precautions, protective equipment and emergency procedures

Wear respiratory protection. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate

personnel to safe areas.

Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

Methods and materials for containment and cleaning up

Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed

containers for disposal.

Reference to other sections

For disposal see section 13.

HANDLING AND STORAGE

Precautions for safe handling

Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.

Normal measures for preventive fire protection.

Conditions for safe storage, including any incompatibilities

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are

opened must be carefully resealed and kept upright to prevent leakage.

Moisture sensitive.

Specific end uses

no data available

EXPOSURE CONTROLS/PERSONAL PROTECTION

Control parameters

Components with workplace control parameters

Exposure controls

Appropriate engineering controls

Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling

the product.

Personal protective equipment

Eye/face protection

Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection

tested and approved under appropriate government standards such as NIOSH (US) or EN

166(EU).

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique

(without touching glove's outer surface) to avoid skin contact with this product. Dispose of

contaminated gloves after use in accordance with applicable laws and good laboratory practices.

Wash and dry hands.

The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and

the standard EN 374 derived from it.

Body Protection

Complete suit protecting against chemicals, The type of protective equipment must be selected

according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection

Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator

with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup

to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air

respirator. Use respirators and components tested and approved under appropriate government

standards such as NIOSH (US) or CEN (EU).

9.1

PHYSICAL AND CHEMICAL PROPERTIES

Information on basic physical and chemical properties

Appearance

Odour

Odour Threshold

Melting point/freezing

point

Initial boiling point and

boiling range

Flash point

Evaporation rate

Form: clear, liquid

Colour: light yellow

no data available

117 °C at 13 hPa - lit.

107 °C - closed cup

no data available

Flammability (solid, gas) no data available

Upper/lower

flammability or

explosive limits

Vapour pressure

Vapour density

no data available

m) Relative density

0,951 g/cm3 at 25 °C

Water solubility

Partition coefficient: n-

octanol/water

Autoignition

temperature

Decomposition

temperature

no data available

Viscosity

Explosive properties

Oxidizing properties

no data available

9.2

10.

10.1

10.2

10.3

10.4

10.5

10.6

11.

11.1

Other safety information

no data available

STABILITY AND REACTIVITY

Reactivity

no data available

Chemical stability

no data available

Possibility of hazardous reactions

no data available

Conditions to avoid

no data available

Incompatible materials

Strong oxidizing agents, Strong acids, Strong bases

Hazardous decomposition products

Other decomposition products - no data available

TOXICOLOGICAL INFORMATION

Information on toxicological effects

Acute toxicity

LD50 Oral - rat - 1.414 mg/kg

Remarks: Gastrointestinal:Changes in structure or function of salivary glands. Cyanosis Respiratory

disorder

LC50 Inhalation - rat - 4 d - 47 mg/m3

Skin corrosion/irritation

Serious eye damage/eye irritation

Eyes - rabbit - Severe eye irritation

Respiratory or skin sensitization

no data available

May cause allergic respiratory and skin reactions

Germ cell mutagenicity

no data available

Carcinogenicity

IARC:

No component of this product present at levels greater than or equal to 0.1% is identified as

probable, possible or confirmed human carcinogen by IARC.

Reproductive toxicity

no data available

Specific target organ toxicity - single exposure

Inhalation - May cause respiratory irritation.

Specific target organ toxicity - repeated exposure

no data available

Aspiration hazard

no data available

Potential health effects

Inhalation

May be fatal if inhaled. Causes respiratory tract irritation.

Ingestion

Skin

Eyes

Harmful if swallowed.

May be harmful if absorbed through skin. Causes skin irritation.

Causes eye burns.

Signs and Symptoms of Exposure

Cough, Shortness of breath, Headache, Nausea, Vomiting, To the best of our knowledge, the chemical,

physical, and toxicological properties have not been thoroughly investigated.

Additional Information

RTECS: CY8545000

12.

12.1

12.2

12.3

12.4

12.5

12.6

13.

13.1

14.

14.1

ECOLOGICAL INFORMATION

Toxicity

no data available

Persistence and degradability

no data available

Bioaccumulative potential

no data available

Mobility in soil

no data available

Results of PBT and vPvB assessment

no data available

Other adverse effects

no data available

DISPOSAL CONSIDERATIONS

Waste treatment methods

Product

Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed

professional waste disposal service to dispose of this material.

Contaminated packaging

Dispose of as unused product.

TRANSPORT INFORMATION

UN number

14.2

ADR/RID: 3382

UN proper shipping name

IMDG: 3382

IATA: 3382

ADR/RID:

IMDG:

IATA:

TOXIC BY INHALATION LIQUID, N.O.S. (2,6-Diisopropylphenyl isocyanate)

Toxic by inhalation liquid, n.o.s. (2,6-Diisopropylphenyl isocyanate)

Passenger Aircraft: Not permitted for transport

Cargo Aircraft: Not permitted for transport

14.3

Transport hazard class(es)

14.4

14.5

14.6

15.

ADR/RID: 6.1

Packaging group

ADR/RID: I

Environmental hazards

ADR/RID: no

Special precautions for user

no data available

REGULATORY INFORMATION

IMDG: 6.1

IMDG: I

IMDG Marine pollutant: no

IATA: 6.1

IATA: -

IATA: no

This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.

15.1

15.2

16.

Safety, health and environmental regulations/legislation specific for the substance or mixture

no data available

Chemical Safety Assessment

no data available

OTHER INFORMATION

Further information

The above information is believed to be correct but does not purport to be all inclusive and
shall be used only as a guide. The information this document is based on the resent state
of our knowledge and is applicable to the product with regard to appropriate safety precautions.
It does not represent any guarantee of the properties of the product. Lookchem shall not be
held liable for any damage resulting from handling or from contact with the above product.
See reverse side of invoice or packing slip for additional terms and conditions of sale.

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