Varenicline tartrate price Varenicline tartrate CAS 375815-87-5 Varenicline tartrate supplier in China
supplier in China
Varenicline tartrate Usage And Synthesis |
Chemical Properties | Tan Solid |
Usage | Nicotinic a4? acetylcholine receptor partial agonist. Aid in smoking cessation. |
Usage | Nicotinic α4β2 acetylcholine receptor partial agonist. Aid in smoking cessation. |
Usage | Varenicline is a prescription medication used to treat smoking addiction. Varenicline is a nicotinic receptor partial agonist. In this respect, it is similar to cytisine and different from the nicotinic antagonist, bupropion, and nicotine replacement ther |
Biological Activity | Orally active, subtype-selective partial agonist at α 4 β 2 nicotinic receptors (K i values are 0.06, 240, 322 and 3540 nM for α 4 β 2, α 3 β 4, α 7, α 1 β γ δ receptors respectively). Reduces nicotine-evoked dopamine release in vitro and decreases nicotine self-administration in vivo . |
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