pharmaceutical felodipine intermediate/72509-76-3/China supplier

Details:

(1) Company Introduction:

 

    Onchem (China) Co.,Ltd  is a comprehensive manufacturer and an international distribution of chemicals throughout the 

 

world. Specialized in APIs, chemical intermediates, herbal extract and pharmaceutical raw materials. our products sell

 

well in Europe, U.S.A., Japan and Korea, Southeast Asia, Taiwan and other country.

 

(2) Product Detailed

 

Name:felodipine 

 

Cas No:72509-76-3

 

MF:C₁₈H₁₉Cl₂NO₄ 

 

Use:calcium antagonist 

 

Appearance:white crystals

 

 

Storage：2 year

 

Sample: we provide free sample.

 

Pharmaceutical felodipine intermediate

 

    Interactions:Recent findings have suggested that felodipine in combination with grapefruit juice can cause toxic effects.

 

Oral administration of felodipine is first metabolized in the gastrointestinal tract and liver by the enzyme CYP3A4.

 

Grapefruit juice contains bergamottin which is found to have an inhibiting effect over this enzyme and as a result the 

 

bioavailability of the drug increases, raising the risk for abnormal side effects.

 

    Contradictions and cautions:contraindicated with allergy to felodipine or other calcium channel blockers, sick sinus

 

syndrome, heart block(second and third degree, lactation. use cautiously with pregnancy, impaired hepatic function

 

 

Delivery: 3days by EMS,FEDEX,DHL.

 

    Welcome to Onchem (China) Co.,Ltd, and welcome to inquiry me about all our products, we will provice the 

 

competitive price for u. We are sincerely responsible for the "product quality" and "After Service"

 

(3) Factory Picture