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paclitaxel 33069-62-4 paclitaxel extract powder
1.99% paclitaxel extract powder
2.Appearance:white powder
3.Fast delivery,high quality
4.free sample,competitive price
1.Introductions of 99% natural paclitaxel extract powder
name : natural paclitaxel extract powder
Appearance:White or almost white crystalline powder
cas no :33069-62-4
molecular formula :C47H51NO14
molecular weight :853.9
2.Main Functions:
Paclitaxel is one of several cytoskeletal drugs that target tubulin. Paclitaxel-treated cells have defects in mitotic
spindle assembly, chromosome segregation, and cell division. Unlike other tubulin-targeting drugs such as
colchicine that inhibit microtubule assembly, paclitaxel stabilizes the microtubule polymer and protects it
from disassembly.
Chromosomes are thus unable to achieve a metaphase spindle configuration. This blocks progression of mitosis, and
prolonged activation of the mitotic checkpoint triggers apoptosis or reversion to the G-phase of the cell cycle
without cell division.
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