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Clarithromycin Clarithromycin 81103-11-9
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High quality Clarithromycin CAS 81103-11-9
Characters:
White or almost white crystalline powder, No odor and bitter.Insoluble in water, freely soluble in chloroform, soluble in acetone or ethyl acetate, sparingly soluble in methanol of alcohol.
Usage:
broad-spectrum tetracycline group of antibiotics.have effect in gram-positive bacterium and negative bacteria, chlamydia and mycobacteria effective, almost can effectively suppress all respiratory pathogen. To stomach acid stability, oral absorption good, high blood drug concentration blood half-life long. Its use were similar to erythromyc,effective in the urinary tract, respiratory tract, skin, ent.
Certificate of analysis for Clarithromycin :
TESTS | USP Specifications | Results |
Appearance | White or almost white crystalline powder, No odor and bitter.Insoluble in water, freely soluble in chloroform, soluble in acetone or ethyl acetate, sparingly soluble in methanol of alcohol. | Conforms |
Identification Tests (IR) | Conforms to the reference spectrum | Conforms |
Specific optical rotation | -89°-95° | -92° |
Crystallinity | Should conform to requirements | Conforms |
PH | Between 7.5 and 10.0 | 8.7 |
Water | ≤2.0% | 0.92% |
Residue on ignition | ≤0.3% | 0.04% |
Residual Solvents | Ethanol≤0.5% | Not detected |
Heavy metals | ≤20ppm | <20ppm |
Assay (HPLC, dried substance) | 9601040ug/mg | 981ug/mg |
Conclusion: Conforms to USP 28 specification for Clarithromycin |
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