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Glimepiride Glimepiride 99% 93479-97-1
Product Details
Name: Glimepiride
CAS No.: 93479-97-1
Formula: C24H34N4O5S
Molecular Weight: 490.62
Density: 1.29 g/cm3
Melting Point: 212.2-214.5 °C
Solubility: DMSO: >10 mg/mL
Appearance: white cyrstalline powder
Usage:
This product is a third generation sulfonylurea antidiabetic drug lasting effect, its mechanism of action is with pancreatic beta cells on the surface of the sulfonyl urea receptor, the receptor and ATP sensitive K + (KATP) channel phase coupling, pushing the KATP channel close, cause cell membrane depolarization, makes the open voltage dependent calcium channel, the flow and prompt the release of insulin in the Ca2 +, and inhibit the synthesis of liver glucose. In addition, Glenn beauty urea can increase by non-insulin-dependent heart glucose uptake, it could be a glucose transporter factor 1, 4 caused by two kinds of protein expression is increased.
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