Details:
Modified GRF (1-29) & (CJC-1295 without
DAC)
Molecular :C152H252N44O42
Molecular
Weight :3367.97
Sequence
:Tyr-D-Asp-Ala-lle-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-lle-Leu-Ser-Arg-NH2
Modified
GRF(1-29) is a Long acting GHRH analog. Growth-hormone-releasing hormone (GHRH),
also known as growth-hormone-releasing fact(GRF GHRF) somatocrinin, is
a 44-amino acid peptide hormone produced in the hypothalamus by the arcuate
nucleus. GHRH has been shown to help stimulate growth hormone (GH) secretion
from the pituitary. GHRH is released in a pulsatile manner, stimulating
pulsatile release of GH respectively.
Modified GRF(1-29) is a synthetic
modification of growth hormone releasing fact(GRF) with D-Ala, Gln, Ala,
Leu substitutions at positions 2, 8, 15, 27 respectively. These
substitutions create a much more stable peptide with the substitution at
position 2 to prevent DPP-IV cleavage, position 8 to reduce asparagine
rearrangement amide hydrolysis to aspartic acid, position 15 to enhance
bioactivity, position 27 to prevent methionine oxidation.
THESE PRODUCTS ARE SOLD FRESEARCH PURPOSES ONLY