Ponatinib 943319-70-8
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Appearance: White powder
Identification: HPLC, HNMR
Loss on drying: ≤0.5%
Residue on ignition: ≤0.5%
Heavy metals(Pb): ≤20ppm
Related Substances: Total Impurities: ≤1.0% ;Any impurity: ≤0.1%
Purity (HPLC): ≥99%
AP24534 is a novel potent,ally available small molecule multitargeted kinase inhibitwith IC50 of 0.37, 2, 1.5, 2.2, 1.1, 10.24 nM fnative pan-BCR-ABL, mutated form, VEGFR2, FGFR1, PDGFRα, mutant FLT3 phosphorylation LYN.
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