AG-014699

Min.Order / FOB Price:Get Latest Price

1 Metric Ton	Negotiable

1 Metric Ton

Negotiable

Min.Order :1 Metric Ton
Purity: >99%
Payment Terms : T/T,

Keywords

AG-014699 Rucaparib 459868-92-9

Quick Details

Appearance:white powder
Application:
PackAge:25kg/drum
ProductionCapacity:1|Metric Ton|Day
Storage:Kept in a cool, dry and ventilated place
Transportation:

Superiority:

Product Name:AG-014699

Synonyms:Rucaparib,PF-01367338，AG-14447,AG014699

Cas No.:459868-92-9

Apperarnce:off-white powder

M.Wt: 421.36

Formula: C19H21FN3O5P

Solubility: Soluble in water

Purity: >99%

Storage: -20℃ 2 years

Details:

AG014699, the phosphate salt of AG14447, which has improved aqueous solubility, has been selected for clinical trial.AG014699 is a tricyclic indole poly(ADP-Ribose) polymerase (PARP) inhibitor with potential antineoplastic activity. PARP-1 inhibitor AG014699 blocks base excision repair mediated by PARP 1 on single strand breaks and may be particularly efficacious in inducing apoptosis in breast cancer associated gene-1 and -2 (BRCA1/2) deficient tumor cells.

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