ABT-888

ABT-888

ABT-888

Min.Order / FOB Price:Get Latest Price

1 Metric Ton

Negotiable

  • Min.Order :1 Metric Ton
  • Purity: >98%
  • Payment Terms : T/T,

Keywords

ABT-888 Veliparib 912444-00-9

Quick Details

  • Appearance:white powder
  • Application:
  • PackAge:25kg/drum
  • ProductionCapacity:1|Metric Ton|Day
  • Storage:Kept in a cool, dry and ventilated place
  • Transportation:

Superiority:

 

Product Name:ABT-888(Veliparib)
Synonyms:MX-1,ABT888 
Cas No.:912444-00-9 
Molecular Formula:C13H16N4O
Molecular Weight:244.29 
Purity:98% 
Apperarnce:white solid 

 

Details:

 

Product Name:ABT-888(Veliparib)
Synonyms:MX-1,ABT888 
Cas No.:912444-00-9 
Molecular Formula:C13H16N4O
Molecular Weight:244.29 
Purity:98% 
Apperarnce:white solid 

Potent inhibitor of PARP-1 and PARP-2 (potency <5nM in vitro). Does not inhibit other NAD-binding enzymes.Has minimal CYP450 inhibition and induction.Shows broad spectrum of chemo- and radiopotentiation. Enantiomeric purity >97% suitable for in vivo studies. Does not show inherent cytotoxicity and shows no single agent activity in tumor models. Has excellent bioavailability and good blood-brain permeation. Increases tumor growth delay resulting from radiation and DNA-damaging agents.

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