High quality Natural Diosmetin 98% powder CAS No.: 520-34-3

Details:

DIOSMETIN Basic information:

Product Name: DIOSMETIN 

Synonyms: 3',5,7-TRIHYDROXY-4'METHOXYFLAVONE;4'-METHOXY-5,7,3'-TRIHYDROXYFLAVONE;4-

METHOXY-5,7,3'-TRIHYDROXYFLAVONE;5,7,3'-TRIHYDROXY-4'-METHOXYFLAVONE;DIOSMETIN;5,7-

dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone;5,7-Dihydroxy-2-[3-hydroxy-4-

methoxyphenyl]-[4H]-1-benzopyran-4-one;4'-Methylluteolin 

CAS: 520-34-3 

MF: C16H12O6 

MW: 300.26 

EINECS: 208-291-8 

Product Categories: Tetra-substituted Flavones;Intermediates & Fine 

Chemicals;Metabolites & Impurities;Pharmaceuticals 

Mol File: 520-34-3.mol 

Introduction:

Diosmin is a flavonoid often administered in the treatment of chronic venous insufficiency, hemorrhoids, and related affections. Diosmin is rapidly hydrolized in the intestine to its aglicone, diosmetin, which is further metabolized to conjugates. In this study, the development and validations of three new methods for the determination of diosmetin, free and after enzymatic deconjugation, and of its potential glucuronide metabolites, diosmetin-3-O-glucuronide, diosmetin-7-O-glucuronide, and diosmetin-3,7-O-glucuronide from human plasma and urine are presented.

Analyses:

Analysis                       Specification             Results                   

Assay(Diosmetin)                98%                   98.20%

Physical control

Appearance                Light Yellow Powder               Complies 

Odor                              Characteristic                          Complies

Sulphated Ash            <0.2%                                        0.14%

Moisture                      <2 %                                            1.7 %           

Particle size              100% pass 80 mesh              Complies    

Heavy metal              <20ppm                                   Complies                   

Pesticides                 Negative                                    Complies    

Microbiological

Total of bacteria            <1000/g                      Complies               

Fungi                              <100/g                        Complies            

Salmonella                  Negative                      Complies             

Coli                               Negative                       Complies

Function:

1.It has effect of Antioxidant, anti-infection and mutagenesis resistance

2.It may restrain enzyme activity of human body CYP1A 

3.Diosmetin is often used in the food, cosmetic and drugs

Package: Vacuum sealed foil packaging,Export grade fiber drum (1kg/bag,25kg/drum). Or according to the customers' request.

Storage: Store in cool & dry place ,do not freeze. Keep away from strong light and heat.