Carboplatin

Details:

Carboplatin

Name:

1,1-Cyclobutanedicarboxylatodiammineplatinum (II)

EINECS:

255-446-0

Molecular Formula:

C6H12N2O4Pt

CAS  No: 41575-94-4

Synonyms:

diammine(1,1-cyclobutanedicarboxylato)-platinum(I; Carboplatin; 1,1-Cyclobutanedicarboxylate diamine platinum(II); Paraplatin; CBDCA; cis-(1,1-Cyclobutanedicarboxylato)diamineplatinum(II); cis-Diamine(1,1-cyclobutanedicarboxylato)platinum(II); Platinum, diamine(1,1-cyclobutanedicarboxylato(2-)-O,O')-,(SP-4-2)-; 1,1-Cyclobutanedicarboxylatodiammineplatinum

InChI:

InChI=1S/C6H8O4.2H3N.Pt/c7-4(8)6(5(9)10)2-1-3-6;;;/h1-3H2,(H,7,8)(H,9,10);2*1H3;/q;;;+2

Molecular Structure:

Chemical Properties

Appearance: white crystalline powder

Molecular Weight: 373.26436

Boiling Point: 366.4oCat 760 mmHg

Melting Point: 228-230oC

Flash Point: 189.6oC

Solubility:  Soluble

Biological Activity:

Antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Enhances radiation-induced single-strand DNA breakage and displays lower nephrotoxicity than analog cisplatin (cis-Diaminodichloroplatinum ).

Stability: Stable. Incompatible with strong oxidizing agents.

Usage:  Analog of Cisplatin with reduced nephrotoxicity. Antineoplastic

Safety Data of 41575-94-4

Safety Statements:  S53;S22;S26;S36/37/39;S45

MSDS infomation:  1,1-Cyclobutanedicarboxylatodiammineplatinum (II) (41575-94-4).msds

Inner package:double PE bags and aluminum-plastic bags

Secondary package:Aluminum drum