15663-27-1 Cisplatin Cisplatin
Product name: Cisplatin
Molecular formula :Cl2(NH3)2Pt
CAS Registry Number :15663-27-1
Standard: USP35/EP7
Appearance: yellow crystalline powder
Purpose: Anticancer drugs
Product name: Cisplatin
Molecular formula :Cl2(NH3)2Pt
CAS Registry Number :15663-27-1
Standard: USP35/EP7
Appearance: yellow crystalline powder
Purpose: Anticancer drugs
Item |
Acceptance criteria |
Result |
Character |
Almost-white or light yellow unfixed powder, smell-less, hygroscopic freely. |
white unfixed powder, smell-less, hygroscopic freely. |
Solubility |
Soluble in water very freely, hardly soluble in ethanol or chloroform or ethyl ether. |
Conforms |
Specific optical rotation |
+10°-+16° |
+12.0° |
Identification |
(1)The product appears flame reaction of sodium salt. (2)UV:Max absorption at 225nm wavelength. (3)IR:Meet the requirements. |
Conform
Conform Meet the requirements. |
PH |
6.5-8.5 |
7.2 |
Clarity and color of solution |
Meet the requirements. |
Conforms |
Related substance |
Max single impurity≤0.1% |
0.036% |
Total impurity≤0.5% |
0.17% |
|
D isomer |
≤0.3% |
Not Detected |
Heavy Metal |
<20ppm |
Conforms |
Water |
7.2%-10.2% |
8.8% |
Chloride |
≤0.02% |
Conforms |
Ethanol |
≤5000ppm |
1687ppm |
Dichloromethane |
≤600ppm |
Not Detected |
N,N-Dimethylformamide |
≤880ppm |
Not Detected |
Purity |
≥99.5% |
99.83% |
Assay |
Not less than 98.50%, calculated on the anhydrous basis. |
99.10% |
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