Fluticasone propionate price Fluticasone propionate CAS 80474-14-2 Fluticasone propionate supplier in China
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Fluticasone propionate Chemical Properties |
mp | 275 °C |
refractive index | 31 ° (C=1, Dioxane) |
storage temp. | Store at RT |
solubility | DMSO: ≥10 mg/mL |
form | solid |
color | white |
Merck | 4211 |
CAS DataBase Reference | 80474-14-2(CAS DataBase Reference) |
Safety Information |
Safety Statements | 22-24/25 |
WGK Germany | 2 |
RTECS | BV7980000 |
MSDS Information |
Provider | Language |
---|---|
Fluticasone propionate | English |
SigmaAldrich | English |
Fluticasone propionate Usage And Synthesis |
Chemical Properties | Crystalline Solid |
Usage | A derivative of Flumethasone. An antiallergic; anti-asthmatic; anti-inflammatory. |
Usage | antiviral |
Usage | An antiallergic and anti inflammatory |
Biological Activity | High affinity, selective glucocorticoid receptor agonist (K d = 0.5 nM). Potently stimulates glucocorticoid receptor-mediated transactivation of gene expression and enhances human eosinophil apoptosis (EC 50 = 3.7 nM) in vitro . Inhibits mast cell accumulation in nasal mucosa following topical administration. Lipophilic, clinically-used anti-inflammatory agent with low oral bioavailability. |
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