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Benzamide,5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy- price Benzamide,5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy- CAS 10238-21-8 Benzamide,5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy- supplier in China
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5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide Chemical Properties |
mp | 173-175°C |
storage temp. | 2-8°C |
Merck | 13,4491 |
CAS DataBase Reference | 10238-21-8(CAS DataBase Reference) |
NIST Chemistry Reference | Glyburide(10238-21-8) |
Safety Information |
Hazard Codes | Xn |
Risk Statements | 20/21/22 |
Safety Statements | 22-36/37/39-36 |
RTECS | YS4725200 |
MSDS Information |
Provider | Language |
---|---|
5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide | English |
ALFA | English |
5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxybenzamide Usage And Synthesis |
Chemical Properties | White Crystalline Powder |
Usage | antihyperglycemic |
Usage | Glyburide is a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic. |
Biological Activity | ATP-dependent K + channel (K ATP ) and CFTR Cl - channel blocker. Inhibits K ATP currents in the pancreas, causing an increase in intracellular Ca 2+ and insulin secretion. Inhibits recombinant CFTR Cl- channels with an IC 50 of 20 μ M. |
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