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4H-1-Benzopyran-4-one,7,8-dihydroxy-2-phenyl- price 4H-1-Benzopyran-4-one,7,8-dihydroxy-2-phenyl- CAS38183-03-8 4H-1-Benzopyran-4-one,7,8-dihydroxy-2-phenyl- supplier in China
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7,8-DIHYDROXYFLAVONE Chemical Properties |
mp | 243-246°C |
storage temp. | Store at +4°C |
CAS DataBase Reference | 38183-03-8(CAS DataBase Reference) |
Safety Information |
Safety Statements | 24/25 |
RTECS | DJ3004000 |
7,8-DIHYDROXYFLAVONE Usage And Synthesis |
Chemical Properties | Yellow Solid |
Usage | 7,8-Dihydroxyflavone is disubstituted flavone that acts as a small-molecule TrkB agonist. 7,8-Dihydroxyflavone has been shown to reverse memory deficits and BACE1 elevation in a mouse model of Alzheim er's disease. 7,8-Dihydroxyflavone may also provide a therapeutic option in the treatment of other neorological disorders such as Rett syndrome and PTSD. |
Usage | vascular protectant, antihaemorrhagic, tyr kinase B agonist |
Biological Activity | Tyrosine kinase receptor B (TrkB) agonist that binds to the extracellular domain of the receptor (K d = 320 nM). Inhibits glutamate-triggered apoptosis in hippocampal neurons in vitro and in vivo . |
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