Irinotecan hydrochl...

Irinotecan hydrochloride trihydrate

Irinotecan hydrochloride trihydrate

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  • Purity: 99
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Keywords

136572-09-3 Irinotecan hydrochloride trihydrate Irinotecan

Quick Details

  • Appearance:Light yellow or almost yellow,crystalline powder and odorless.
  • Application:API
  • PackAge:1kg/drum
  • ProductionCapacity:10000|Metric Ton|Day
  • Storage:low temperature
  • Transportation:air/courier

Superiority:

Irinotecan hydrochloride trihydrate

 

CAS No.

136572-09-3

Chemical Name:

Irinotecan hydrochloride trihydrate

Synonyms:

Irinotecan Trihydrate;Irinotecan Hydrochlorid;IRINOTECON HCL TRIHYDRATE;IRINOTECAN HCL TRIHYDRATE;trihydrate,(s)-hydrochlorid;Irinotecan Hydrochloride Irinotecan Hydrochloride (100 mg);Irinotecan HCl Trihydrate (CaMpto);IRINOTECAN HYDROCHLORIDE TRIHYDRATE;IRINOTECAN MONOHYDROCHLORIDE TRIHYDRATE

CBNumber:

CB6122430

Molecular Formula:

C33H45ClN4O9

Formula Weight:

677.18

MOL File:

136572-09-3.mol

Irinotecan hydrochloride trihydrate Property

mp :

250-256°C (dec.)

CAS DataBase Reference:

136572-09-3

 

 

 

Details:

Irinotecan hydrochloride trihydrate

 

CAS No.

136572-09-3

Chemical Name:

Irinotecan hydrochloride trihydrate

Synonyms:

Irinotecan Trihydrate;Irinotecan Hydrochlorid;IRINOTECON HCL TRIHYDRATE;IRINOTECAN HCL TRIHYDRATE;trihydrate,(s)-hydrochlorid;Irinotecan Hydrochloride Irinotecan Hydrochloride (100 mg);Irinotecan HCl Trihydrate (CaMpto);IRINOTECAN HYDROCHLORIDE TRIHYDRATE;IRINOTECAN MONOHYDROCHLORIDE TRIHYDRATE

CBNumber:

CB6122430

Molecular Formula:

C33H45ClN4O9

Formula Weight:

677.18

MOL File:

136572-09-3.mol

Irinotecan hydrochloride trihydrate Property

mp :

250-256°C (dec.)

CAS DataBase Reference:

136572-09-3

 

 

TEST

SPECIFICATIONS

RESULT

 

ASSAY

  (on dried basis)

 98.0%--102.0%

100.1%

 

CHARACTERS

Light yellow or almost yellow,crystalline powder and odorless.

Conforms

 

IDENTIFICATION

The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation,as obtained in the Assay.

Conforms

 

Infrared Absorption:In accordance with the reference Standard spectrum of Irinotecan Hydrochloride.

Conforms

 

Meet the requirements of the identification tests for chlorides.

Conforms

 

RESIDUE ON IGNITION

NMT 0.1 %

0.03 %

 

HEAVY METALS

NMT 0.001 %

<0.001%

 

WATER(K.F)

7.0 %—9.0 %

8.3 %

 

RELATED COMPOUNDS (HPLC) (on dried basis)

7-Desethyl  irinotecana≤0.15%

Undetected

 

Irinotecan related compound Ab≤0.15%

Undetected

 

11-Ethyl irinotecanc≤0.15%

Undetected

 

Camptothecind≤0.15%

Undetected

 

Irinotecan related compound Be≤0.15%

Undetected

 

7-Ethyl camptothecinf≤0.15%

Undetected

 

7,11-Diethyl-10-hydroxycamptothecing≤0.15%

0.08%

 

Any unspecified impurity≤0.10%

0.08%

 

Total impurities≤0.5%

0.17%

 

CONCLUSION

The product is in accordance with USP36 to test the above-mentioned items, the test results conform to the specification.

 

 

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