CasNo.144060-53-7,Febuxostat,Febuxostat(144060-53-7) Suppliers

1 Kilogram	Negotiable

144060-53-7 Febuxostat febuxostat

Molecular Structure:
Name:	Febuxostat
CAS No.:	144060-53-7

Formula:	C₁₆H₁₆N₂O₃S
Molecular Weight:	316.3748
Synonyms:	5-Thiazolecarboxylic acid, 2-(3-cyano-4-(2-methylpropoxy)phenyl)-4-methyl-;Tei 6720;Febuxostat/ 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid;Febuxostat (JAN/USAN);TMX 67;Tei-6720;2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid;TMX-67;
EINECS:
Density:	1.31 g/cm³
Melting Point:	238-239 °C
Boiling Point:	536.6 °C at 760 mmHg
Flash Point:	278.3 °C
Solubility:
Appearance:	crystalline solid

Molecular Structure:
Name:	Febuxostat
CAS No.:	144060-53-7

Formula:	C₁₆H₁₆N₂O₃S
Molecular Weight:	316.3748
Synonyms:	5-Thiazolecarboxylic acid, 2-(3-cyano-4-(2-methylpropoxy)phenyl)-4-methyl-;Tei 6720;Febuxostat/ 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid;Febuxostat (JAN/USAN);TMX 67;Tei-6720;2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid;TMX-67;
EINECS:
Density:	1.31 g/cm³
Melting Point:	238-239 °C
Boiling Point:	536.6 °C at 760 mmHg
Flash Point:	278.3 °C
Solubility:
Appearance:	crystalline solid

Analytical Results
Item	Acceptance criteria	Result
Appearance	White to almost white crystalline powder, odorless	White crystalline powder, odorless
Solubility	Easily soluble in N,N-Dimethylformamide, soluble in Dimethyl sulfoxide. Sparingly soluble in Chloroform.Sligt soluble in methanol, practically insoluble in water	Conforms
m.p.	207℃~211℃	207.5℃~208.5℃
Identification	(1) In content test, principal peak in test solution is similar in retention time to reference.	Conforms
	(2)UV:Max absorption at 215nm and 315nam, min absorption at 265nm	Conforms
	(3)IR: Spectrum sample should be consistent with spectrum of reference standard	Conforms
Related substances	ImpurityⅠNMT0.1%	N.D.
	ImpurityⅡNMT0.1%	N.D.
	ImpurityⅢNMT0.1%	N.D.
	ImpurityⅣNMT0.1%	0.02%
	Any other impurity NMT0.1%	0.06%
	Total impurities: NMT 0.5%	0.11%
Water	≤2.0%	0.5%
Residue on ignition	≤0.1%	0.02%
Heavy metals	≤20ppm	Conforms
Residual Solvents	Ethanol≤5000ppm	23ppm
	Tetrahydrofuran≤720ppm	N.D.
	N-hexane≤290ppm	N.D.
	N,N-Dimethylformamide≤880ppm	N.D.
	Dichloromethane≤600ppm	24ppm
Assay	98.0%~102.0%（Calculated as anhydrous basis）	99.2%