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Rocuronium bromide /119302-91-9
Product Name: |
Rocuronium bromide
|
Synonyms: |
[3-Hydroxy-10,13-dimethyl-2-morpholin-4-yl-16-(1-prop-2-enyl-2,3,4,5-tetrahydropyrrol-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate bromide; (2beta,3alpha,5alpha,16beta,17beta)-17-(acetyloxy)-3-hydroxy-2-(morpholin-4-yl)-16-[1-(prop-2-en-1-yl)pyrrolidinium-1-yl]androstane; (2beta,3alpha,5alpha,16beta,17beta)-17-(acetyloxy)-3-hydroxy-2-(morpholin-4-yl)-16-[1-(prop-2-en-1-yl)pyrrolidinium-1-yl]androstane bromide |
CAS RN.: |
119302-91-9 |
EINECS: | 214-776-5 |
Molecular Weight: | 609.6782 |
Molecular Formula: | C32H53BrN2O4 |
Functions:Muscle relaxation medicine. The nondepolarizing neuromuscular blockers. Used for patients in hospital and clinic general anesthesia and conventional tracheal intubation of auxiliary medicine,can make surgery and mechanical entilation skeletal muscle relaxation during.
Specification:
Solubility |
Freely soluble in water and anhydrous ethanol |
Complied |
Identification |
|
|
a) IR Spectrum (KBr) b) Bromide Test |
Must comply with Ep5.4 Must comply with Ep5.4 |
Complied Complied |
Test |
|
|
Appearance Of Solution |
|
Complied |
Specific Optical Rotation |
Between +28.5°~+32.0° |
+30.8° |
pH |
Between 8.9~9.5 |
9.1 |
Heavy Metals |
Not more than 10ppm |
Complied |
Water Content |
Not more than 4.0% |
3.1% |
Sulphated ash |
Not more than 0.1% |
0.06% |
chlorides |
Not more than 0.1% |
0.07% |
Total impurities |
Not more than 1.5% |
1.1% |
unkonwn impurities(each) |
Not more than 0.1% |
0.05% |
Impurity A |
Not more than 0.2% |
0.13% |
Impurity B |
Not more than 0.3% |
Nil |
Impurity C |
Not more than 0.3% |
0.23% |
ImpurityD |
Not more than 0.1% |
Nil |
Impurity E |
Not more than 0.1% |
Nil |
Impurity F |
Not more than 0.1% |
0.03% |
Impurity G |
Not more than 0.1% |
Nil |
Impurity H |
Not more than 0.1% |
Nil |
Residual Solvents |
|
|
Acetonitrile |
Not more than 410ppm |
27ppm |
Dichloromethane |
Not more than 600ppm |
19ppm |
Assay of Rocuronium Bromide On Anhydrous Basis |
Not less than 99.0% and not more than 101.0% |
99.4% |
Conclusion:The Sample Complies With Specification Of Ep6 |
CAS NO:15170-74-8
CAS NO:15170-74-8
CAS NO:15170-74-8
CAS NO:15170-74-8
CAS NO:15170-74-8
CAS NO:15170-74-8
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