475207-59-1

475207-59-1

475207-59-1

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  • Purity: 99%

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Sorafenib tosylate

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475207-59-1
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Sorafenib tosylate Basic information
Product Name: Sorafenib tosylate
Synonyms: SORAFENIB TOSYLATE;Sorafenib & its intermediates;Sorafinib mesylate;4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide monomethanesulfonate;Sorafenib Tosylate(Bay 43-9006,Nexavar);2-PyridinecarboxaMide, 4-[4-[[[[4-chloro-3-(trifluoroMethyl)phenyl]aMino]carbonyl]aMino]phenoxy]-N-Methyl-, 4-Methylbenzenesulfonate;Sorafenib Tosylate (Nexavar);Sorafenib (Nexavar)
CAS: 475207-59-1
MF: C21H16ClF3N4O3.C7H8SO3
MW: 637.03
EINECS:  
Product Categories: Bay 43-9006
Mol File: Mol File
 
 
Sorafenib tosylate Chemical Properties
CAS DataBase Reference 475207-59-1(CAS DataBase Reference)
 
Safety Information
 
MSDS Information
 
 
Sorafenib tosylate Usage And Synthesis
Usage Sorafenib Tosylate (Bay 43-9006, Nexavar) is a small molecular inhibitor of VEGFR, PDGFR, c-Raf and B-Raf with IC50s of 18 nM, 10 nM, 3 nM and 15 nM, respectively.
Usage Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively

 

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