Tretinoin 302-79-4 ...

Tretinoin 302-79-4 Vitamin A acid

Tretinoin 302-79-4 Vitamin A acid

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25 Kilogram

FOB Price: USD 1580.0000

  • Min.Order :25 Kilogram
  • Purity: 99%
  • Payment Terms : T/T,,MoneyGram,Other

Keywords

Tretinoin Vitamin A acid 302-79-4

Quick Details

  • Appearance:White crystalline powder
  • Application:1 Tretinoin is the acid form of vitamin A and is also known as all-trans retinoic acid or ATRA. It is a drug commonly used to treat acne vulgaris and keratosis pilaris. It is available as a cream or g
  • PackAge:25 kgs/ fiber drum or according to customer's demand
  • ProductionCapacity:20|Metric Ton|Month
  • Storage:Store in cool & dry place not freeze., keep away from strong light and heat
  • Transportation:deliver within1-5 days by DHL,FedEx,AIR,SEA

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Details:

Tretinoin ; Retinoic acid
CAS Number 302-79-4 

Product

Tretinoin (Retinoic acid)

Appearance

yellow or light orange crystalline powder

Cas No.

302-79-4

Molecular formula:

C20H28O2

    Molecular weight : 300.44

Synonyms:

3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid; all-trans-Retinoic acid; Vitamin A acid; Retionoic Acid; Tretinoin (Retionoic Acid); Tretinion ; N,N'-hexane-1,6-diyldiacetamide; retinoic acid; (9cis)-retinoic acid; (11cis,13cis)-7,8-dihydroretinoic acid; 15-oxidoretinal

Specification

98.0~102.0%

 

Structure

 

 

 Factory Provide Best (Retinoic acid) Tretinoin

 

 

Function

1 Tretinoin is the acid form of vitamin A and is also known as all-trans retinoic acid or ATRA. It is a drug commonly used to treat acne vulgaris and keratosis pilaris. It is available as a cream or gel It is also used to treat acute promyelocytic leukemia.

 

2 Its success in treating acute promyelocytic leukemia was a major breakthrough in the treatment of this type of leukemia.It works in APL because the majority of cases involve a chromosomal translocation of chromosomes 15 and 17, which causes genetic fusion of the retinoic acid receptor gene to the promyelocytic leukemia  gene. This fusion PML-RAR protein is responsibl

 

3. for preventing immature myeloid cells from differentiating into more mature cells. This block in differentiation is thought to cause leukemia. ATRA acts on PML-RAR to lift this block, causing the immature promyelocytes to differentiate to normal mature blood cells thus decreasing promyelocytes.

 

 

 

 

 

 

 

 

 

 

 

 

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