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1 Kilogram |
Negotiable |
Folic acid Folic Folic acid USP
USP
Folic acid
Characteristics |
A yellowish or orange, crystalline powder. Practically insoluble in water and in most organic solvents. It dissolves in dilute acids and in alkaline solutions. |
|
Identification |
A: Specific optical rotation |
+18 to +22 (anhydrous substance) |
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B:HPLC chromatograms |
Complies |
|
C:TLC Identification |
Complies |
Related substance |
Impurity A not more than 0.5% |
|
|
Impurity D not more than 0.6% |
|
|
any other impurity not more than 0.5% |
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|
Total of other impurity not more than 1.0% |
|
UV absorption ratio |
A256/A365:2.80-3.0 |
|
Free amines |
NMT 1/6 |
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Organic volatile impurities |
Conforms |
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Chromatographic purity |
Not more than2.0% |
|
Sulphated ash |
Not more than 0.2% |
|
Water |
5.0 %- 8.5 % |
|
Assay |
96.0-102.0% (anhydrous basis) |
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