Acetamide,N-(4,5-di...

Acetamide,N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)-

Acetamide,N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)-

Min.Order / FOB Price:Get Latest Price

1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,T/T,,MoneyGram,Other

Keywords

Acetamide,N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)-? price Acetamide,N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)-? CAS 87-11-6 Acetamide,N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)-? supplier in China

Quick Details

  • Appearance:Yellow solid
  • Application:antitumour activity. Thiolutin is a potent inhibitor of bacterial and yeast RNA polymerases, and also inhibits mannan and glucan formation in fungi. Thiolutin suppresses tumour cell-induced angiogenes
  • PackAge:1kg/bag, 1kg/drum or 25kg/drum or as per your request.
  • ProductionCapacity:1|Metric Ton|Month
  • Storage:Stored in cool, dry and ventilation place; Away from fire and heat
  • Transportation:as per your request

Superiority:

superior quality

Details:

THIOLUTIN Chemical Properties
storage temp.  −20°C
solubility  DMSO: 5 mg/mL
 
Safety Information
Hazard Codes  T+,T
Risk Statements  28
Safety Statements  45
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  JP1355000
MSDS Information
 
 
THIOLUTIN Usage And Synthesis
Chemical Properties Yellow solid
Usage Thiolutin is an antibiotic first described by Tanner and co-workers in 1950. Resurgent interest in this class of microbial metabolites was stimulated by the discovery of their selective antitumour activity. Thiolutin is a potent inhibitor of bacterial and yeast RNA polymerases, and also inhibits mannan and glucan formation in fungi. Thiolutin suppresses tumour cell-induced angiogenesis in vivo.
Usage Thiolutin is an antibiotic isolated from several strains of Streptomyces albus. Thiolutin is a natural dithiol that reversibly inhibits bacterial and yeast RNA polymerases.
Biological Activity Antibiotic; inhibits bacterial RNA polymerase. Inhibits adhesion of HUVEC cells to vitronectin (IC 50 = 0.83 mM) and subsequently reduces paxillin levels. Suppresses tumor cell-induced angiogenesis.

 

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