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4H-1-Benzopyran-4-one,5,6,7-trihydroxy-2-phenyl-? price 4H-1-Benzopyran-4-one,5,6,7-trihydroxy-2-phenyl-? CAS 491-67-8 4H-1-Benzopyran-4-one,5,6,7-trihydroxy-2-phenyl-? supplier in China
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Baicalein Chemical Properties |
mp | 256-271 °C(lit.) |
storage temp. | 2-8°C |
Merck | 14,942 |
BRN | 272683 |
CAS DataBase Reference | 491-67-8(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xi,Xn |
Risk Statements | 36/37/38-20/21/22 |
Safety Statements | 26-36 |
WGK Germany | 3 |
Hazard Note | Irritant |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
ALFA | English |
Baicalein Usage And Synthesis |
Chemical Properties | Yellow Crystalline Solid |
Usage | antiviral (HIV) |
Usage | An inhibitor of 12-lipoxygenase, leukotriene biosynthesis and release of lysosomal enzymes. It also inhibits cellular Ca2+ uptake and mobilization and adjuvant-induced arthritis. Baicalein is the fl avonoid component of Nepalese and Sino-Japanese crude drugs. |
Usage | inhibitor of lipoxidase and leukotriene biosynthesis |
Biological Activity | Inhibitor of 5- and platelet 12-lipoxygenases (IC 50 values are 9.5 and 0.12 mM respectively). Also inhibits Raf-mediated MEK-1 phosphorylation in C6 rat glioma cells and induces G1 and G2 cell cycle arrest by decreasing cdk1, cdk2, cyclin D2 and cyclin A expression. Anti-inflammatory in vivo . |
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