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Riluzole producer 1744-22-5 6-TRIFLUOROMETHOXY-BENZOTHIAZOL-2-YLAMINE
Riluzole Basic information
Product Name: Riluzole
Synonyms: 2-Amino-6-(trifluoromethoxy)-1,3-benzothiazole 97%;2-Amino-6-(trifluoromethoxy)-1,3-benzothiazole97%;Riluzole(GMPofSFDA);CBI-BB ZERO/001785;BUTTPARK 13\02-09;6-TRIFLUOROMETHOXYBENZOTHIAZOLE-2-YL-AMINE;6-(TRIFLUOROMETHOXY)-1,3-BENZOTHIAZOL-2-AMINE;6-TRIFLUOROMETHOXY-BENZOTHIAZOL-2-YLAMINE
CAS: 1744-22-5
MF: C8H5F3N2OS
MW: 234.2
EINECS:
Product Categories: Neuroprotective;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;GABA/Glycine receptor;Glutamate;Amines;Heterocycles;Sulfur & Selenium Compounds;RILUTEK
Mol File: 1744-22-5.mol
Riluzole Chemical Properties
mp 116-118°C
storage temp. Store at RT
solubility DMSO: ≥25 mg/mL
form solid
color white
Safety Information
Hazard Codes T,Xi
Risk Statements 25
Safety Statements 45
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS DL2830000
Hazard Note Irritant
HazardClass IRRITANT
MSDS Information
Riluzole Chemical Properties
mp 116-118°C
storage temp. Store at RT
solubility DMSO: ≥25 mg/mL
form solid
color white
Safety Information
Hazard Codes T,Xi
Risk Statements 25
Safety Statements 45
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS DL2830000
Hazard Note Irritant
HazardClass IRRITANT
MSDS Information
Riluzole Usage And Synthesis
Chemical Properties White Crystalline Solid
Usage A neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant.
Usage anticonvulsant, glutamate release inhibitor, anti-ALS
Usage A neuroprotective agent. A glutamate release inhibitor. An anticonvulsant
Biological Activity Novel psychotropic agent with anticonvulsant, hypnotic, anxiolytic, anti-ischemic and anesthetic properties. Riluzole is able to act as a glutamate release inhibitor, blocks voltage-dependent Na + channels and inhibits GABA uptake by striatal synaptosomes.
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