Zein

Details:

Zein Chemical Properties
Melting point     266-283°C
solubility     Practically insoluble in acetone, ethanol, and water; soluble in aqueous alcohol solutions, aqueous acetone solutions (60–80% v/v), and glycols. Also soluble in aqueous alkaline solutions of pH 11.5 and above.
Merck     10119
CAS DataBase Reference    9010-66-6
EPA Substance Registry System    Zeins (9010-66-6)
Safety Information
Safety Statements     22-24/25
WGK Germany     3
F     21
HS Code     35040090
MSDS Information
Provider    Language
Zein    English
SigmaAldrich    English
ACROS    English
Zein Usage And Synthesis
Chemical Properties    White to slightly yellow powder; odorless; tasteless. Free of cystine, lysine, and tryptophan. A resinous material dispersible in water with neutral sulfonated castor oil; soluble in dilute alcohol; insoluble in water, dilute acids, anhydrous alcohols, turpentine, esters, oils, fats. Nontoxic protein of the prolamine class, derived from corn; contains 17 amino acids. Combustible.
Chemical Properties    Zein is a prolamin obtained from corn (Zea mays Linne' (Fam. Gramineae)). It occurs as a granular, straw- to pale yellow-colored amorphous powder or fine flakes and has a characteristic odor and bland taste.
Uses    Paper coating, grease-resistant coating, label varnishes, laminated board, solid-color prints, printing inks, food coatings, microencapsulation, fibers.
Uses    Zein is a corn protein produced from corn gluten meal. it lacks the amino acids, lysine and tryptophan, so it is not suitable as a sole source of dietary protein. it is insoluble in water and alcohols but is soluble in aqueous alcohols, glycols, and glycol ethers. it functions as a film and coating to provide a moisture barrier for nuts and grain products. it also functions as a coating for confections and a glaze for panned goods.
Production Methods    Zein is extracted from corn gluten meal with dilute propan-2-ol.
Pharmaceutical Applications    Zein is used as a tablet binder in wet-granulation processes or as a tablet-coating agent mainly as a replacement for shellac. It is used primarily as an enteric-coating agent or in extended-release oral tablet formulations and other delivery systems. Zein is also used in food applications as a coating agent.
Safety Profile    When heated to decomposition it emits acrid smoke and irritating fumes.
Safety    Zein is used in oral pharmaceutical formulations and food products, and is generally regarded as an essentially nontoxic and nonirritant material at the levels employed as an excipient. However, it may be harmful if ingested in large quantities.
storage    Zein should be stored in an airtight container, in a cool, dry place. It has not been reported to polymerize.
Incompatibilities    Incompatible with oxidizing agents.
Regulatory Status    GRAS listed. Included in the FDA Inactive Ingredients Database (oral tablets). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Zein Preparation Products And Raw materials
Raw materials    PETROLEUM ETHER