94-09-7 Benzocaine ETHYL P-AMINOBENZOATE
Product Name: Benzocaine
Synonyms: AETHOFORM;anesthesin;AKOS BBS-00003658;4-AMINOBENZOIC ACID ETHYL ESTER;LABOTEST-BB LTBB000527;H-4-ABZ-OET;ETHYL 4-AMINOBENZOATE;ETHYL P-AMINOBENZOATE
CAS: 94-09-7
MF: C9H11NO2
MW: 165.19
EINECS: 202-303-5
Product Categories: Aromatic Esters;C8 to C9;Carbonyl Compounds;Esters;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Research Chemical;Pharmaceutical intermediate;API;Pharma materials;Intermediate of Tetracaine hydrochloride
Mol File: 94-09-7.mol
Benzocaine Structure
Benzocaine Chemical Properties
Melting point 88-90 °C
Boiling point 172 °C (12.7517 mmHg)
density 1.17
Fp 172°C/13mm
storage temp. 0-6°C
Merck 14,1086
BRN 638434
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference 94-09-7(CAS DataBase Reference)
NIST Chemistry Reference Benzoic acid, 4-amino-, ethyl ester(94-09-7)
EPA Substance Registry System Benzoic acid, 4-amino-, ethyl ester(94-09-7)
Safety Information
Hazard Codes Xi,T,F
Risk Statements 43-36/37/38-39/23/24/25-23/24/25-11
Safety Statements 22-24/25-37/39-26-24-45-36/37-16-7
WGK Germany 2
RTECS DG2450000
PackingGroup III
HS Code 29224995
Hazardous Substances Data 94-09-7(Hazardous Substances Data)
Benzocaine Usage And Synthesis
Lipid soluble surface anaesthetic Benzocaine is a fat soluble surface anaesthetic. Compared with several other local anesthetics such as lidocaine, tetracaine, etc., the strength of effect is small. Owing to its playing role in mucosal, people feel comfort. It is a fat soluble and strong drug, therefore it is easy to combine with the lipid layer of the mucosa or skin, but not easily go through the human body to produce toxic.
Benzocaine is the precursor materials of Ousso imitation, Orthocaine, procaine. At the same time, it is used as a local anesthetic in medicine, and has analgesic, antipruritic effect, mainly used for wounds, ulcers, mucosal surfaces and hemorrhoids narcotic pain and itch. The ointment can also be used for relieving pain and lubrication to nasopharyngeal catheter and the process of PEEP mirror. Temporary relieve pain and itching skin in the wounds of mild burns, sunburn, trauma and insect bites. Ears are used to reduce the pain and itching of acute congestive, concentrated otitis, swimming, and external use. Also it is effective to toothache, sore throat, oral ulcers, hemorrhoids, anal fissure, vulva Sao. As Male Genital Desensitizer make ejaculation slow. Or used as a lubricant for the anesthesia of the catheter and the endoscope.
Uses 1.The goods are used to relieve pain for the local anesthetic, wounds, ulcers and hemorrhoids facial, also are cough suppressants retreat intermediates.
2.Used in cosmetic ultraviolet absorption, local anesthetics and used to relieve pain in the wound, ulcer surface and Hemorrhoids.
Methods of production The goods are got in the way that p-Nitro-ethylbenzoate is reduced by iron [99-77-4].
Chemical property It is Colorless oblique square crystal. Melting point is 92℃ (88-90℃), boiling point is 183-184 (1.87kPa). 1g of the product is soluble in water, 5ml ethanol, 2ml, 4ml, 2500ml, 30-50ML, or almond oil and olive oil, also soluble in dilute acid. Stable in the air, no smell, taste bitter.
Chemical Properties white odourless crystals
Usage A commonly used topical pain reliever. Main active ingredient in anesthetic ointments.
Usage Anesthetic;Na+ channel blocker
Usage Benzocaine is used as an anesthetic (local).
Benzocaine Preparation Products And Raw materials
Preparation Products 4-Fluorobenzoic acid-->Benzonatate-->Ethyl 4-(butylamino)benzoate
Raw materials 4-Aminobenzoic acid-->4-Aminophthalic acid-->Ethyl p-nitrobenzoate
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