443-48-1 Metronidazole BP2015
Synonyms: 1-(2-Hydroxy-1-ethyl)-2-methyl-5-nitroimidazole;1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole;1-(beta-Hydroxyethyl)-2-methyl-5-nitroimidazole;1-(beta-Oxyethyl)-2-methyl-5-nitroimidazole;1H-Imidazole-1-ethanol, 2-methyl-5-nitro-;1H-Imidazole-1-ethanol,2-methyl-5-nitro-;1-Hydroxyethyl-2-methyl-5-nitroimidazole;2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethanol
CAS: 443-48-1
MF: C6H9N3O3
MW: 171.15
EINECS: 207-136-1
Product Categories: Active Pharmaceutical Ingredients;API's;Peptide Synthesis/Antibiotics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;FLAGYL;antibiotic;Pharmaceutical intermediates
Mol File: 443-48-1.mol
Metronidazole Structure
Metronidazole Chemical Properties
Melting point 159-161 °C(lit.)
storage temp. 2-8°C
solubility acetic acid: 0.1 M, clear, faintly yellow
form crystalline
Water Solubility <0.1 g/100 mL at 20 ºC
Merck 6157
Stability: Stable. Incompatible with strong oxidizing agents.
NIST Chemistry Reference Metronidazole(443-48-1)
EPA Substance Registry System 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-(443-48-1)
Safety Information
Hazard Codes Xn,T,F
Risk Statements 40-46-45-39/23/24/25-23/24/25-11
Safety Statements 36/37-45-53-16-7
WGK Germany 3
RTECS NI5600000
F 8
HS Code 29332990
Hazardous Substances Data 443-48-1(Hazardous Substances Data)
Metronidazole Chemical Properties
mp 159-161 °C(lit.)
storage temp. 2-8°C
solubility acetic acid: 0.1 M, clear, faintly yellow
form crystalline
Water Solubility <0.1 g/100 mL at 20 ºC
Merck 6157
Stability: Stable. Incompatible with strong oxidizing agents.
NIST Chemistry Reference Metronidazole(443-48-1)
EPA Substance Registry System 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-(443-48-1)
Safety Information
Hazard Codes Xn,T
Risk Statements 40-46-45
Safety Statements 36/37-45-53
WGK Germany 3
RTECS NI5600000
F 8
HS Code 29332990
Hazardous Substances Data 443-48-1(Hazardous Substances Data)
Metronidazole Usage And Synthesis
Chemical Properties white to slightly yellow crystalline powder
Usage Used as an antibacterial in the treatment of rosacea. Antiprotozoal (trichomonas). A potential human carcinogen.
General Description White to pale-yellow crystalline powder with a slight odor. Bitter and saline taste. pH (saturated aqueous solution) about 6.5.
Air & Water Reactions Insoluble in water.
Reactivity Profile Metronidazole darkens on exposure to light. Metronidazole is incompatible with strong oxidizing agents. .
Fire Hazard Flash point data for Metronidazole are not available; however, Metronidazole is probably combustible.
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