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ω-Conotoxin MVIIA: inhibits Cav2.2 ω-Conotoxin MVIIA has been isolated from the venom of the cone Conus magus. Omega-conotoxins act at presynapti…
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ω-Conotoxin MVIIA: inhibits Cav2.2 ω-Conotoxin MVIIA has been isolated from the venom of the cone Conus magus. Omega-conotoxins act at presynaptic membranes, they bind and block voltage-sensitive calcium channels (VSCC). This toxin blocks N-type calcium channels (Cav2.2/CACNA1B). ω-conotoxin MVIIA is available under the name Prialt by Neurex. It blocks acute pain in patients who no longer obtain relief from opiate drugs. It is 100 to 1.000 times more potent than morphine. This toxin blocks calcium channels and disables nerves that transmit pain signals. Purity rate: > 97 % Price: 100μg - 100 euros
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