Simvastatin

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Purity: 99.10 %

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Appearance:A white crystalline powder
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Product name:Simvastatin CAS NO. :79902-63-9 TEST RESULT Description A white crystalline powder. Usages A competitive inhibitor of HMG-CoA re…

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Product name:SimvastatinCAS NO. :79902-63-9TEST RESULT Description A white crystalline powder. Usages A competitive inhibitor of HMG-CoA reductase. A synthetic analog of lovastatinSolubility Practically insoluble in water, very soluble in methylene chloride, freely soluble in alcohol. Identification A. Specific Optical Complies. Rotation Complies. B. Infrared Absorption Appearance of solution 1 % solution in methanol is clear and not more intensely colour than BY7 standard. Specific Optical Rotation + 291 o Heavy Metal < 20 ppm Loss on Drying ( at 60 o C for 3 0.23 % Hrs. ) under vacuum Sulphated Ash 0.01 % Related Substances ( By HPLC ) A. Hydroxy Acid 0.10 % B. Acetate Ester 0.19 % C. AnhydroSimvastatin NIL D. Dimer 0.05 % E. Lovastatin & F. 0.18 % Epilovastatin 0.43 % Sum of all the area of all peaks apart from principle peak and peak due to Lovastatin & Epilovastatin. Assay of Simvastatin , C25H38O5 99.10 %

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