Product name:Metformin Hcl Crystalline CAS NO. :657-24-9 TESTS OBSERVATIONS Characters White Fine Powder. Solubility Freely soluble i…
Product name:Metformin Hcl CrystallineCAS NO. :657-24-9 TESTS OBSERVATIONS Characters White Fine Powder. Solubility Freely soluble in water, slightly soluble in alcohol, practically insoluble in acetone and in methylene chloride. Identification A. Melting Point 224 o C B. IR Positive C. By TLC Conforms D. Colouration with α- napthol Complies E. Reaction of Chlorides Positive Appearance of Solution Solution S is clear and colourless. Related Substances ( By HPLC ) A. Cyanoguanidine 0.004 % B. Other Impurity 0.039 % Heavy Metals Less than 10 ppm. Loss on Drying 0.22 % Sulphated Ash 0.05 % Assay on dry basis 99.42 % Additional Test Particle Size 98.61 % passing through 100 mesh.
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