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Lurasidone 367514-87-2 Pharmaceutical Chemicals
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Name | Lurasidone | |
Synonyms | (3aR,4S,7R,7aS)-2-[[(1R,2R)-2-[[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione | |
Molecular Structure | ||
Molecular Formula | C28H36N4O2S | |
Molecular Weight | 492.68 | |
CAS Registry Number | 367514-87-2 |
Lurasidone may be useful for treating the cognitive and memory deficits seen in schizophrenia. In animal studies, it reverseddizocilpine-induced learning and memory impairment and was found to be superior in doing this to all of the other antipsychotics examined, including risperidone, olanzapine, quetiapine, clozapine, aripiprazole, and haloperidol. Lurasidone has activity at several serotonin receptors that are involved in learning and memory, and unlike most other antipsychotics, lacks anyanticholinergic effects (which are known to impair cognitive processes and memory).These properties may underlie its improved effectiveness in treating these symptoms relative to older agents.
Systematic (IUPAC) name: (3aR,4S,7R,7aS)-2-[((1R,2R)-2-{[4-(1,2-benzisothiazol-3-yl)-piperazin-1-yl]methyl}cyclohexyl)methyl]hexahydro-1H-4,7-methanisoindol-1,3-dione.
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