（GMP）Octreotide Acetate 83150-76-9

Details:

Product Name: Octreotide Acetate

Octreotide Acetate CAS No. 83150-76-9

Octreotide Acetate synonyms:

L-cysteinamide,D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-(2-hydroxy-1-(hydroxymethyl) propyl)-cyclic (2->7)-disulfide, (R-(R*,R*))

Octreotide Acetate main functions:

Octreotide Acetate is used for the treatment of growth hormone producing tumors (acromegaly and gigantism), pituitary tumors that secrete thyroid stimulating hormone(thyrotropinoma), diarrhea and flushing episodes associated with carcinoid syndrome, and diarrhea in people with vasoactive intestinal peptide-secreting tumors (VIPomas).

Octreotide Acetate is often given as an infusion for management of acute haemorrhage from esophageal varices in liver cirrhosison the basis that it reduces portal venous pressure, though current evidence suggests that this effect is transient and does not improve survival.

Octreotide Acetate is used in nuclear medicine imaging by labelling with indium-111 (Octreoscan) to noninvasively image neuroendocrine and other tumours expressing somatostatin receptors.[3] More recently, it has been radiolabelled with carbon-11[4] as well as gallium-68, enabling imaging withpositron emission tomography (PET), which provides higher resolution and sensitivity.

Octreotide Acetate can also be labelled with a variety of radionuclides, such as yttrium-90 or lutetium-177, to enablepeptide receptor radionuclide therapy (PRRT) for the treatment of unresectable neuroendocrine tumours.

Inchi：

InChI=1/C49H66N10O10S2/c1-28(61)39(25-60)56-48(68)41-27-71-70-26-40(57-43(63)34(51)21-30-13-5-3-6-14-30)47(67)54-37(22-31-15-7-4-8-16-31)45(65)55-38(23-32-24-52-35-18-10-9-17-33(32)35)46(66)53-36(19-11-12-20-50)44(64)59-42(29(2)62)49(69)58-41/h3-10,13-18,24,28-29,34,36-42,52,60-62H,11-12,19-23,25-27,50-51H2,1-2H3,(H,53,66)(H,54,67)(H,55,65)(H,56,68)(H,57,63)(H,58,69)(H,59,64)

Molecular formula: C₄₉H₆₆N₁₀O₁₀S₂

Molecular weight: 1139.35g/mol

Octreotide Acetate density: 1.395g/cm³

Octreotide Acetate boiling point: 1447.228℃ at 760mmHg

Octreotide Acetate refractive index: 1.673

Octreotide Acetate flash point: 829.053℃

Package: 25kg/drum

Octreotide Acetate appearance: white powder

Assay：≧98%