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Lansoprazole Usage And Synthesis |
Chemical Properties | White Crystalline Powder |
Usage | anthelmintic |
Usage | A H+,K+-ATPase inhibitor that displays antisecretory activity |
Usage | Used as a gastric proton pump inhibitor. An antiulcerative |
Biological Activity | H + ,K + -ATPase inhibitor (IC 50 = 6.3 μ M) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC 50 = 0.09 μ M for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacterial against Helicobacter pylori in vitro . Also blocks swelling-dependent chloride channel (ICIswell) in NIH3T3 fibroblasts. More potent than omeprazole (5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole ). |
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