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Other Names: p-Nitrobenzoic acid/4-Nitrobenzoic acid EINECS No.: 200-526-2 Place of Origin: China (Mainland)
p-Nitrobenzoic acid (CAS NO.62-23-7) is widespread used in explosive and dyestuff industries and as a chemical intermediate. p-Nitrobenzoic acid was tested using the p-Nitrobenzoic acid protocol to follow up on preliminary data from a 13-week prechronic study that found testicular atrophy and estrous cycle irregularities in B6C3F1 mice and as a structure-activity study in conjunction with other nitrobenzoic acids. Data from a 2-week dose-range-fnding study (Task 1) were used to set exposure concentrations for the Task 2 continuous cohabitation study at 0.35, 0.75, and 1.50% in feed. Based on mean feed consumption and body weight, the estimated daily dosages were approximately 0.5, 1.1, and 2.4 g/kg/day.
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