2627-69-2 AICAR(Acadesine) supplier of AICAR(Acadesine)
Name : AICAR(Acadesine)
CAS NO.: 2627-69-2
usage: glucose uptake stimulant; AMPK activator
AICAR
CAS 2627-69-2
Formula C9H14N4O5
Molecular Weight 258.23
purity 99%MIN
Assay HPLC;LC-MS;HNRM
Appearance white powder
Usage
AICAR also known as ZMP is an analog of AMP that is capable of stimulating AMP-dependent protein kinase activity (AMPK). AICAR is being clinically used to treat and protect against cardiac ischemic injury. If left untreated, it may lead to a myocardial infarct. Cardiac Ischemia is caused by insufficient blood flow and oxygen to the myocardium .The drug was first used in the 1980’s as a method to preserve blood flow to the heart during surgery. Currently, the drug has also been shown as a potential treatment for diabetes by increasing the metabolic activity of tissues by changing the physical composition of muscle.
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