Levulinic Acid 123-76-2 intermediate for medicines

Details:

Applications:
Levulinic acid has a wide range of applications. Levulinic acid can react as a carboxylic acid or as a ketone, through esterification, halogenation, hydrogenation, oxidative dehydrogenation, condensation, etc., to produce a variety of products, including resins, pharmaceuticals, fragrances, solvents, coatings and inks, rubber and plastic additives, lubricating oil additives, surfactants, etc. In the pharmaceutical industry, its calcium salt (calcium fructoconate) can be used to make intravenous injections. As a nutritional drug, it helps to form bones and maintain the normal excitability of nerves and muscles, and is also used to produce indomitacin and plant hormones. The bisphenol acid obtained from levulinic acid can be used to produce water-soluble resin, which can be used to produce filter paper in paper industry. Levulinic acid is also an intermediate of pesticides and dyes.

Preparation:
The invention relates to a method for separating levulinic acid from monosaccharide hydrolysate and a method for extracting and separating high purity levulinic acid from monosaccharide hydrolysate by ion exchange resin adsorption. The technical scheme is as follows: Using monosaccharide hydrolysate as starting material, high content of levulinic acid is obtained by column chromatography, atmospheric concentration and vacuum rectification;

The whole separation process is as follows:

1) The weak basic anion exchange resin is loaded into the column by wet method and pre-treated for reserve use; The monosaccharide hydrolysate was passed through the chromatographic column with a flow rate of 0.5 ~ 3.0 times the bed volume/hour and a temperature of 20 ~ 40℃.

2) Flush the chromatographic column with deionized water to wash the neutral impurities in the monosaccharide hydrolysate at a flow rate of 0.5 ~ 3.0 times the bed volume/hour at a temperature of 20 ~ 40℃ ，

3) The levulin adsorbed on the resin was acid-washed off with 0.1 ~ 1.0mol/l eluent, the flow rate was 0.3 ~ 2.0 times the bed volume/hour, and the temperature was 20 ~ 40℃; The eluent was collected separately, the flow fraction of pure levulinic acid was combined, the concentration at atmospheric pressure and rectification at 0.01 ~ 0.05MPa were used to obtain high levulinic acid content.

Melting Point	30-33 °C
Boiling Point	245-246 °C
Density	1.134 g/mL at 25 °C
Vapor Pressure	1 mm Hg ( 102 °C)
Refractive Index	n20/D 1.439
Flashing Point	280 °F
Storage Condition	Store below +30°C
Solubility	675 g/L in water

Our advantages:

1) Timely communication, reply within 12 hours.You can leave any messages on our whatsapp or send email to us.

2)Selecting raw materials strictly,our products are the highest purity.

3)Reasonable and competitive price.

4) Free sample for your evaluation.Customers only need to undertake the shipping fee for delivery the samples to your destionation.

5)OEM/ODM Available.Trial order is available for testing after samples.

6) Packaging can be customized according to each buyers' special request.

We guarantee that your package will pass 100% through the Mexico US, UK, Australia, Netherlands, Canada, France, Germany, Spain, Belgium, Sweden, Poland, Russian, Ukraine, Kazakhstan, Czech Republic, Slovakia, Portugal.

 

We have freight forwarders in these countries, and our customs clearance company will clear your parcels without any customs issues, sometimes even 1000 kg. Door to door service. Make sure you receive 100% of the goods. Let you have a good experience of our strong freight capacity.

Company Introduction

hebei yanxi chemical  co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and development production of reagent tens of thousands of species. our aim is quality strives for the survival. Seek development by credit reputation. Our products have big price advantage in Europe South America and so on .and Our company also has the advantage of high quality in Africa. in the past two years our products has reached more than 30 countries in the world, Europe. South America. North America, southeast Asia, Africa, etc. We welcome all over the world with the best quality and lowest price friend common cooperation and common development!

After Sales Service

 1) Best quality in your requirement

 2)Competitive price in china market

 3)Mature technical support

 4)Professional logistic support

 5 )Full experience of large numberscontainers loading in chinese sea port

 6 )Fast shipment by reputed shipping line

 7) Packing with pallet as buyer's special request

 8) Best service after shipment.

 9) Cargoes together with container after-sales service available

 10) Full experience in export

 11)Raw materials from chinese origin

FAQ

 

What is the way you ship

Express: FedEx, UPS, EMS, DHL, USPS, TNT, DPD, Aramex etc

Our way of shipping the products is universal and secure.

The company name and other contents related to pharmacy are not written on the package slips.

The way of packing is regularly changed for a secure delivery.

The packages are small in order to avoid unwelcomed questions . If the order is big, then it will be divided into two or more packages

 

Can the packages be trackable

YES, we provide tracking number and you can track on internet.

 

Where do you ship to

Worldwide.

 

Do you offer domestic shipping/remail shipping

Yes we can ship to USA/UK/Canada/Australia/Germany etc warehouse first then to you.

 

Do you ensure your packing , what about customs, what happens if the package is retained

We concern a lot about our safety system, we pack the orders as secure as possible. If a package is seized at customs, reships of seized orders will be done provided you have a copy of the letter to show us. If you receive a seizure letter, please contact us immediately with a scanned copy of the seizure letter, and also a new address to have your order reshipped to.

 

Which payment options are available

Bitcoin

Bank wire

MoneyGram