Amlodipine Besylate

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1 Metric Ton	Negotiable

1 Metric Ton

Negotiable

Amlodipine Besylate Intermediates of Glibenclamide competitive price

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Amlodipine besilate Chemical Properties

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English

Amlodipine besilate Usage And Synthesis

Chemical Properties	White Crystalline Solid
Usage	A dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive
Usage	Angiotensin II inhibitor prodrug, antihypertensive
Usage	Amlodipine besylate is a L-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. Amlodipine also inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats.
Biological Activity	L-type calcium channel blocker that displays antihypertensive properties. Inhibits Ca 2+ -induced contractions in depolarized rat aorta (IC 50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC 50 = 25 μ M).