high quality INCB024360

Min.Order / FOB Price:Get Latest Price

1 Gram	FOB Price: USD 9.0000

1 Gram

FOB Price: USD 9.0000

Min.Order :1 Gram
Purity: 99%min
Payment Terms : T/T,

Keywords

INCB024360 914471-09-3 Pharmaceutical Chemicals

Quick Details

Appearance:White powder
Application:lab research
PackAge:10g/pack,100g/pack,1kg/pack
ProductionCapacity:10000|Kilogram|Year
Storage:storage in a dry, ventilated place under normal
Transportation:BY EMS,FEDEX,AIR

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Details:

INCB024360 is an orally available hydroxyamidine and inhibitor of indoleamine 2,3-dioxygenase (IDO1), with potential immunomodulating and antineoplastic activities. INCB024360 targets and binds to IDO1, an enzyme responsible for the oxidation of tryptophan into kynurenine. By inhibiting IDO1 and decreasing kynurenine in tumor cells, INCB024360 increases and restores the proliferation and activation of various immune cells, including dendritic cells (DCs), NK cells, and T-lymphocytes, as well as interferon (IFN) production, and a reduction in tumor-associated regulatory T cells (Tregs). Activation of the immune system, which is suppressed in many cancers, may inhibit the growth of IDO1-expressing tumor cells. IDO1 is overexpressed by a variety of tumor cell types and DCs

only for lab resarch

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