Trospium chloride

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Chemical name: (1R,3r,5S)-3-[(Hydroxydiphenylacetyl)oxy]spiro[8-azoniabicyclo[ 3.2.1]octane-8,1￠- pyrrolidinium] chloride. Structural formula: …

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Chemical name: (1R,3r,5S)-3-[(Hydroxydiphenylacetyl)oxy]spiro[8-azoniabicyclo[ 3.2.1]octane-8,1￠- pyrrolidinium] chloride. Structural formula: Molecular formula: C25H30ClNO3 Molecular weight: 428.0 Property: White or almost white, crystalline powder. Very soluble in water, freely soluble in methanol, practically insoluble in methylene chloride. Specification: Standard EP6.0 Appearance:White or almost white, crystalline powder. Appearance of solution:Solution S is clear and not more intensely coloured than reference solution B7.. pH :5.0 to 7.0. Related Substances: Impurity A: Not More Than 0.3%. Impurity B: Not More Than 0.5%. Impurity C: Not More Than 0.5%. Any other Related compounds:Not More Than 0.1%. Total Related Compounds:Not More Than 1.0%. Loss on drying: Not more than 0.5% Reidue on ignition: Not more than 0.1% Assay:99.0% to 101.0% calculated on the anhydrous basis Use:Treatment of Overactive bladder(OAB).

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