ML 161

Min.Order / FOB Price:Get Latest Price

100 Gram	FOB Price: USD 1.0000

100 Gram

FOB Price: USD 1.0000

Min.Order :100 Gram
Purity: 98%
Payment Terms : L/C

Keywords

ML 161 ML 161;2-BroMo-N-[3-[(1-oxobutyl)aMino]phenyl]benzaMide;2-BroMo-N-(3-butyraMidophenyl)benzaMide;Benzamide, 2-bromo-N-[3-[(1-oxobutyl)amino]phenyl]-;ML 161 2-Bromo-N-[3-[(1-oxobutyl)amino]phenyl]benzam 423735-93-7

Quick Details

Appearance:off white powder
Application:CAS:423735-93-7; Small molecule inhibitors,
PackAge:100g,500g,1kg,25kg
ProductionCapacity:1000|Gram|Month
Storage:refrigerate
Transportation:shipping

Superiority:

We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research.

We are committed to provide excellence in researching, manufacturing and drug discovery process.

Our research team of scientists consists of western-trained Ph.D.s with experience and capabilities in drug R&D methodologies and medicinal chemistry.

Details:

生物活性	ML-161是一种蛋白酶活化受体1 (PAR1)的别构抑制剂，对人血小板中血小板P-选择素表达抑制的IC50为0.26μM。
体外研究	ML-161是PAR1的别构抑制剂。ML-161抑制凝血酶诱导的血小板活化，通过P-Selectin表达测定，这种作用具有剂量依赖性。ML-161通过PAR1而选择性抑制SFLLRN和凝血酶诱导的血小板聚集，但对AYPGKF，血栓素，或ADP诱导的血小板聚集没有影响。