Fenretinide, 4-HPR N-(4-HYDROXYPHENYL)-ALL-TRANS RETINAMIDE;N-(4-HYDROXYPHENYL)RETINAMIDE;RETINOIC ACID P-HYDROXYANILIDE;RETINAMIDE;hpr;n-(4-hydroxyphenyl)-retinamid;4-HYDROXYPHENYLRETINAMIDE;4HPR 65646-68-6
Fenretinide (4-HPR) is a synthetic retinoid deriverative. 4-HBR is shown to exhibit binding to the retinoic acid receptors (RAR) at concentrations necessary to induce cell death.
IC50 value:
Target: RAR
Retinoids are substances related to vitamin A. It has been investigated for potential use in the treatment of cancer, as well as in the treatment of cystic fibrosis, rheumatoid arthritis, acne, psoriasis, and has been found to also slow the production and accumulation of a toxin that leads to vision loss in Stargardt's patients.
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