Paroxetine hydrochloride Paroxetine hcl 78246-49-8
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1.Product description
Product Name: Paroxetine hydrochloride
CAS: 78246-49-8
MF: C19H21ClFNO3
MW: 365.83
2.Physical properties
Paroxetine hydrochloride is an odorless, off-white powder, having a melting point range of 120° to 138°C and a solubility of 5.4 mg/mL in water.
3.Specification
Appearance |
White or almost white crystalline powder |
Conform |
Identification |
A. Comparing with the spectrum obtained with CRS |
Conform |
|
B. The principal peak obtained with the test solution is similar in retention and size to that obtained with the reference solution |
Conform |
|
C. Water (by KF) |
Conform |
|
D. Reaction of chlorides |
Conform |
Impurity D |
≤0.2% |
|
Related substances |
1) Impurity A: not more than 0.3% |
0.03% |
|
2) Unspecified impurities: For each impurity, not more than 0.10 % |
|
|
3) Total impurities: not more than 0.5% |
|
Heavy metals |
≤0.002% |
<0.002% |
Water |
2.2%~2.7% |
2.50% |
Sulfated ash |
≤0.1% |
<0.1% |
Assay(anhydrous substance) |
97.5%~102.0% |
100.20% |
Residual solvents |
Meets the requirements |
Conform |
4.Application
Paroxetine Hcl is primarily used to treat major depression, obsessive-compulsive disorder (OCD), Post-
traumatic stress disorder (PTSD). etc. It was first antidepressant formally approved in the US for treatment of
panic attacks
5.Packing
25KG/Drum or as per your requirement
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