Amlodipine besilate

Amlodipine besilate

Amlodipine besilate

Min.Order / FOB Price:Get Latest Price

1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,,MoneyGram,Other

Keywords

Amlodipine besilate Amlodipine besilate 111470-99-6

Quick Details

  • Appearance:White or almost white powder
  • Application:A dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive
  • PackAge:25kg/drum or acc to customers' request
  • ProductionCapacity:200|Metric Ton|Month
  • Storage:Store at RT
  • Transportation:1.By airplane 2.By sea 3.By express way(DHL,TNT,FEDEX..ETC) 4.acc to customers' request

Superiority:

Our Advantages: 

GMP factory

Full experience of large numbers containers loading in main Chinese seaports 

Packing with pallet as buyer's special request 

Best service after shipment with e-mail 

Cargos together with container sales seervice available 

Rich experience for exporting

Cargos photo before and after loading into container

Raw materials from chinese origin

Hefei TNJ Chemical Industry Co., limited(ISO 9001: 2008), are strong in the field of Pharmaceuticals, 
food additives, plant extract and fine chemicals for more than 10 years.

 

Service we can provide: 

1). Mixed container: We can mix different items in one container.

2). Quality control: Before shipment, we can provide free sample for test. Inspection before shipping.

3). Packing: We can pack according to your requirements and also give you some other packing methods for reference and suggest adequate packing methods according to global trend. We will send you photo of goods before shipment.

4). Prompt shipment: We usually can ship the goods within 7 days for 1*20'FCL conatiner after order confirmed and also provide professional shipping documents for your Customs clearance.

5). We work closely with DHL, FEDEX, UPS,ETC., we can ship samples and small quantity goods to you fast and safe.

We work closely with famous airline companies like BA,PO,OZ,CX,UPS,LA,TG,TA,ET,etc. and professional vessel companies like MSK,"K"LINE,CMA,CSAV,ZIM,WANHAI,HAMBURG-SUD,etc. We can ship bulk quantity to you quick and safe.

6). We can provide door to door shipment in many countries. 

Details:

1.Product description

Product Name: Amlodipine besilate

CAS: 111470-99-6

MF: C26H31ClN2O8S

MW: 567.05

 

2.Physical properties

(1) Melting Point: 199-201 °C 

(2) solubility: DMSO: 20 mg/mL  

(3) Flash Point: 272.6 °C 

(4) Enthalpy of Vaporization: 80.17 kJ/mol  

(5) Boiling Point: 527.2 °C at 760 mmHg 

(6) Vapour Pressure of Amlodipine besylate:3.34E-11 mmHg at 25 °C

 

3.Specification

 

Specification

Appearance

White or almost white powder

Identification

Meets the requirements

Specific Rotation

-0.10 ~ +0.10°

Water

≤0.5%

Heavy Metals

≤0.002%

Redidue in Ignition

≤0.2%

Related Substances

Meets the requirements

Benzene Sulfonic Acid

27.3 ~ 28.7%

Ethanol

≤300ppm

Toluene

≤60ppm

Benzene

≤2ppm

Acetic Acid

≤600ppm

Methylamine

≤20ppm

Ethyl Benzene Sulfonate

≤5ppm

Particle Size

Meets the requirements

Assay

98.0 ~102.0%

Standard

USP33

 

 

4.Application

A dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive

Angiotensin II inhibitor prodrug, antihypertensive

Amlodipine besylate is a L-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. Amlodipine also inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats.

Biological Activity L-type calcium channel blocker that displays antihypertensive properties. Inhibits Ca 2+ -induced contractions in depolarized rat aorta (IC 50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC 50 = 25 μ M).

 

5.Packing

25KG/Drum or as per your requirement

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