Isoniazid Isoniazid 54-85-3
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Packing with pallet as buyer's special request
Best service after shipment with e-mail
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Cargos photo before and after loading into container
Raw materials from chinese origin
Hefei TNJ Chemical Industry Co., limited(ISO 9001: 2008), are strong in the field of Pharmaceuticals,
food additives, plant extract and fine chemicals for more than 10 years.
Service we can provide:
1). Mixed container: We can mix different items in one container.
2). Quality control: Before shipment, we can provide free sample for test. Inspection before shipping.
3). Packing: We can pack according to your requirements and also give you some other packing methods for reference and suggest adequate packing methods according to global trend. We will send you photo of goods before shipment.
4). Prompt shipment: We usually can ship the goods within 7 days for 1*20'FCL conatiner after order confirmed and also provide professional shipping documents for your Customs clearance.
5). We work closely with DHL, FEDEX, UPS,ETC., we can ship samples and small quantity goods to you fast and safe.
We work closely with famous airline companies like BA,PO,OZ,CX,UPS,LA,TG,TA,ET,etc. and professional vessel companies like MSK,"K"LINE,CMA,CSAV,ZIM,WANHAI,HAMBURG-SUD,etc. We can ship bulk quantity to you quick and safe.
6). We can provide door to door shipment in many countries.
1.Product description
Product Name: Isoniazid
CAS: 54-85-3
MF: C6H7N3O
MW: 137.14
EINECS: 200-214-6
2.Physical properties
White crystalline powder
mp 171-173 °C(lit.)
Fp >250°C
storage temp. Refrigerator
Water Solubility 14 g/100 mL (25 ºC)
Sensitive Air Sensitive
Merck 14,5186
BRN 119374
Stability: Stability Stable, but may be air or light sensitive. Combustible. Incompatible with strong oxidizing agents, chloral, aldehydes, iodine, ferric salts, hypochlorites.
3.Specification
Test Item |
Analysis Specification |
Result |
Description |
crystalline powder |
Conforms |
Melting range |
129°C~132°C |
130.8°C-131°C |
Loss on drying |
≤0.5% |
0.20 % |
Specific rotation |
-58°~-62°(C=1,in CH3OH) |
-61.05° |
Sulphated ash |
≤0.1% |
0.08 % |
Heavy metals |
≤10ppm |
Conforms |
Chlorides |
≤0.02% |
Conforms |
Sulfates |
≤0.02% |
Conforms |
Fluorine |
14.7%~17.9% |
15.2% |
Residual solvent |
Methanol ≤0.2% Isopropanol ≤0.2% Ethyl acetate≤0.2% Chloroform ≤0.2% |
0.0% 0.0% 0.0% 0.0% |
Related substances (HPLC) |
Single impurity ≤0.2% Total impurities ≤0.5% |
0.05% 0.08% |
Assay |
≥99.5% |
99.92% |
Conclusion |
Accordance with the reference
|
4.Application
antibacterial, tuberculostatic
Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Sele ctively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antib acterial (tuberculostatic).
For the treatment of all forms of tuberculosis in which organisms are susceptible.
5.Packing
25KG/Drum or as per your requirement
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