Topiramate

Topiramate
Topiramate
Topiramate

Topiramate

Min.Order / FOB Price:Get Latest Price

25 Kilogram

Negotiable

  • Min.Order :25 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,D/P,T/T,

Keywords

Topiramate 97240-79-4 Topamax

Quick Details

  • Appearance:White to off-white powder
  • Application:Central Nervous System Agents
  • PackAge:25kg/drum for commercial quantity.Specific packing required by customer
  • ProductionCapacity:5000|Metric Ton|Month
  • Storage:
  • Transportation:by sea or by air

Superiority:

ISO

Specifications

97240-79-4 Topiramate 
Topiramate in stock 
High quality Topiramate 
Topiramate powder

TESTING SPECIFICATION

USP 32

ITEM TESTED

STANDARD

Appearance

White to off-white powder. Freely soluble in dichloromethane

 Identification

Infrared Absorption

The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation , as obtained in the Assay

Specific rotation

Between -28.6° and -35.0°,measured at 20°

Water

Not more than 0.5%

Residue on Ignition

Not more than 0.1%

Heavy metals

Not more than 10ppm

Related compounds by HPLC

(Test 1)

Fructose not more than 0.3%

Compound A not more than 0.3%

Other individual impurity not more than 0.1%

Total impurities not more than 0.5%

Limit of sulfamate and sulfate

Sulfamate ion not more than 0.10%;

Sulfate ion not more than 0.10%.

Assay                                                                

Topiramate contains not less than 98.0% and not more than the equivalent of 102.0% of C12H21NO8S, calculated with reference to the Anhydrous Basis.

 

 

Details:

1, Introduction of Topiramate

Topiramate, with the systematic name of beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate, is one kind of white powder. This chemical belongs to the Product Categories which include Active Pharmaceutical Ingredients; APIs; Health & Beauty; Carbohydrates & Derivatives; Pharmaceuticals; Glutamate receptor. It is used as an anticonvulsant and an antidepressant. It is also used to treat Post Traumatic Stress Disorder.

2. Properties of Topiramate


Topiramate has the properties:

(1)Molecular Formula: C12H21NO8S;

(2)Molecular Weight: 339.362040 g/mol;

(3)Index of Refraction: 1.497;

(4)Molar Refractivity: 74.32 cm3;

(5)Molar Volume: 253.8 cm3;

(6)Surface Tension: 53.3 dyne/cm;

(7)Density: 1.336 g/cm3;

(8)Flash Point: 219.1 °C;

(9)Enthalpy of Vaporization: 69.55 kJ/mol;

(10)Boiling Point: 438.7 °C at 760 mmHg;

(11)Vapour Pressure: 6.76E-08 mmHg at 25 °C;

(12)Melting Point: 125°C ;

(13)DMSO Solubility : ~44 mg/mL;

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